A comparative study of dexmedetomidine vs clonidine as an adjuvent to local anaesthetic drug in supraclavicular brachial plexus block.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- This prospective and observational study will help us to compare the efficacy between Inj. Bupivacaine and Inj Clonidine vs Inj Bupivacaine and Inj dexmedetomidine Improving the duration and Quality of analgesia
Study Overview
Brief Summary
A COMPARATIVE OF DEXMEDETOMIDINE VS CLONIDINE AS AN ADJUVANT TO LOCAL ANAESTHETIC DRUG IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK
OBJECTIVE:To observe and compare Onset and duration of sensory and motor block, To observe and compare Duration of analgesia,To compare Perioperative hemodynamic changes & any adverse effects
INCLUSION CRITERIA:
Patient willing to sign inform consent.
ASA grade I and II patients posted for elective upper limb surgeries under
Supraclavicular Brachial Plexus Block
Age: 18-65 years
EXCLUSION CRITERIA:Patient refusal
Infection at local site
Hypersensitivity or Allergy to local anaesthetic agent
Coagulation disorders
Patient on Anticoagulants
Alcoholic or patient with drug abuse
Patients receiving any drug that interact with our study drug
Pre Existing Nerve injury
Inadequate effect of nerve block or supplemented with other type of
anaesthesia
SAMPLE SIZE AND GROUP
Group-1 :Patients who have received inj. Bupivacaine 0.5% 20 ml with inj. Dexmedetomidine 0.5 mcg/kg through PNS or USG machine guided supraclavicular block.
Group-2: patients who have received inj. Bupivacaine 0.5% 20 ml with inj. Clonidine 0.5 mcg/kg through PNS or USG machine guided supraclavicular block.
•Study site: S.B.K.S. Medical Institute and Research Centre, Sumandeep Vidhyapeeth University, Piparia, Vadodara, Gujarat.
•Study duration: This study will be done for a periods of 18 months.
Study design: comparative observational study
LIKELY OUTCOME / BENEFITS OF STUDY
This prospective and observational study will help us to compare the efficacy between Inj. Bupivacaine and Inj Clonidine vs Inj Bupivacaine and Inj dexmedetomidine Improving the duration and Quality of analgesia, Reducing dose of bupivacaine so reduce toxicity, some provide sedation haemodynamic responses to anaesthesia by having better outcome in haemodynamics.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patient willing to sign inform consent.
- •ASA grade I and II patients posted for elective upper limb surgeries under Supraclavicular Brachial Plexus Block.
Exclusion Criteria
- •Patient refusal Infection at local site Hypersensitivity or Allergy to local anaesthetic agent Coagulation disorders Patient on Anticoagulants Alcoholic or patient with drug abuse Patients receiving any drug that interact with our study drug Pre Existing Nerve injury Inadequate effect of nerve block or supplemented with other type of anaesthesia.
Outcomes
Primary Outcomes
This prospective and observational study will help us to compare the efficacy between Inj. Bupivacaine and Inj Clonidine vs Inj Bupivacaine and Inj dexmedetomidine Improving the duration and Quality of analgesia
Time Frame: reversal of sensory and motor blockage and VAS score after giving blockage at following time point: | 0 min | 30 min | 1 hr | 2 hr | 3 hr | 4 hr | 5 hr | 7 hr | 10 hr
Secondary Outcomes
- Analgesia and haemodynamic responses to anaesthesia by having better outcome in haemodynamics(At end of surgery)
Investigators
Paresh M Chaudhary
Smt.Bhikiben Kanjibhai Shah Medical Institute and Research Centre