Using DNIC to Predict Acupuncture Therapy Outcome: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Diffuse Noxious Inhibitory Control Efficiency
研究概览
简要总结
The investigators hypothesize that acupuncture modifies the DNIC efficiency and that DNIC can serve as a predictor to identify 'good responders' to acupuncture early in therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy women with a progesterone-coated intrauterine device (Mirena), and
- •Men greater than or equal to 18 years old.
排除标准
- •Acupuncture treatment in the previous six weeks, to discount any persisting effect of acupuncture.
- •Treatment of a pain condition with pain medication.
- •Regular use of benzodiazepines.
- •Skin diseases, such as scleroderma, psoriasis or eczema.
- •An adverse event due to acupuncture therapy.
- •Pregnant women.
- •Women without a progesterone-coated intrauterine device (Mirena).
- •Anyone older than 60 years of age, fatigued, with a pacemaker ICD, artificial joint, prolonged bleeding time/hemophilia, open wounds, or a known susceptibility to profound analgesia after acupuncture treatment.
研究组 & 干预措施
Acupuncture
14 weeks of electroacupuncture therapy.
干预措施: Acupuncture (Other)
结局指标
主要结局
Diffuse Noxious Inhibitory Control Efficiency
时间窗: Week 0, 2, 4, 6, and 12 of acupuncture therapy
The efficiency of diffuse noxious inhibitory control (DNIC) is a measure of one's ability to inhibit pain perception. DNIC efficiency is assessed by a psychophysical test that involves a heat thermode as the "test stimulus" and a warm water bath as the "conditioning stimulus". The results of this test will be used as the primary outcome measure.
次要结局
未报告次要终点
研究者
Ruth Landau
Professor, Director of OB Anesthesia & Clinical Genetics Research
University of Washington