Factors Affecting the Results of Treatment of Patients With Colorectal Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Mortality rate
研究概览
简要总结
The study attempts to quantify the relative risks for mortality, anastomotic leakage and other early and late postoperative complications, recurrence rate, cancer-specific survival, recurrence-free survival after colorectal surgery for patients with colorectal cancer depending on the localization of the tumor.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically proven primary adenocarcinoma of bowel;
- •All patients who have indications for surgical treatment of colorectal cancer based on the decision of the oncological council;
- •Signed informed consent with agreement to attend all study visits;
排除标准
- •Unresectable tumor or contradictions to surgery;
- •Indications for chemotherapy or radiation therapy prior to surgery;
- •Patient withdrawal from the trial or loss of follow-up;
- •Emergent operation;
- •Pregnancy.
结局指标
主要结局
Mortality rate
时间窗: 3 years after surgery
the overall mortality after colorectal cancer surgery
Anastomotic leakage rate
时间窗: 3 months after surgery
Anastomotic leakage rate after colorectal resection. AL is confirmed by one or more of the following conditions: * fecal discharge from the pelvic drainage at any time after surgery * rectovaginal fistula defined as fecal or mucus discharge from the vagina * pelvic sepsis as defined by the collection of pus/ fecal material in the pelvis documented by CT scan * contrast present outside of the anastomosis as seen by X-Ray contrast enema proctography or CT contrast enema proctography
次要结局
- Recurrence rate(3 years after surgery)
- 30-day complication rate(30 days after surgery)
- Cancer-specific survival(3 years after surgery)
- Recurrence-free survival(3 years after surgery)