Effects of Liquid Zinc Supplementation and Dispersible Zinc Tablets on Plasma Zinc Concentration
Not Applicable
Completed
- Conditions
- Zinc Deficiency
- Interventions
- Dietary Supplement: Liquid placebo supplementDietary Supplement: Liquid zinc syrupDietary Supplement: Zinc tablet
- Registration Number
- NCT00944853
- Lead Sponsor
- University of California, Davis
- Brief Summary
The study aims to compare the effects of two different formulations of zinc supplements on plasma zinc concentrations among young Burkinabe children.
- Detailed Description
1) To investigate the effects of short-term zinc supplementation, provided either as a dispersible tablet containing zinc sulfate ("ZinCfant," Nutriset Ltd; Malaunay, France) or as a liquid ZnSO4 solution, on changes in serum zinc concentration, compared with a placebo in young Burkinabe children; and 2) to assess the relationship between change in serum zinc concentration and the presence of altered intestinal permeability within each treatment group.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 462
Inclusion Criteria
- currently breast feeding
- informed consent of a parent or guardian.
Exclusion Criteria
- symptomatic acute or chronic febrile infections
- diarrhea within the past week
- consuming vitamin or mineral supplements or zinc-fortified infant formulas
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Liquid placebo supplement Liquid placebo supplement provided daily Zinc syrup Liquid zinc syrup Liquid Zinc Syrup (ZnSO4) solution provided daily Zinc tablet Zinc tablet Dispersible zinc tablets provided daily
- Primary Outcome Measures
Name Time Method Plasma zinc concentration 3 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Toussiana Health District
🇧🇫Toussiana, Burkina Faso