Sleep quality in critically ill patients on proportional assist ventilation with load-adjustable gain factors (PAV+) vs pressure support (PS) - a randomised controlled cross-over trial

Cretan Critical Care Society (Greece)0 sites10 target enrollmentNovember 11, 2009

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Sleep quality in critically ill patients on mechanical ventilation
Sponsor: Cretan Critical Care Society (Greece)
Enrollment: 10
Status: Completed
Last Updated: 11 years ago

No summary available.

Registry

who.int

Start Date

November 11, 2009

End Date

TBD

Last Updated

11 years ago

Study Type

Interventional

Sex

All

Sponsor

Cretan Critical Care Society (Greece)

•Critically ill patients (\>18 years old, both males and females) who are receiving mechanical ventilation for at least 48 hours will be studied. At the time of the study all patients will be haemodynamically stable and ventilated on PS through cuffed endotracheal or tracheostomy tubes with anticipated further mechanical ventilation of at least 24\-h duration. All patients must achieve a score of 0 on the Richmond Agitation Sedation Scale (RASS) either with or without intravenous (IV) propofol.

•1\. Anticipated ICU stay \<24 h
•2\. Premorbid diseases that could confuse interpretation of sleep monitoring including central nervous system (CNS) diseases and sleep disorders
•3\. Haemodynamic instability (BP \<90 mmHg despite therapy)
•4\. Glasgow Coma Scale \<11 and acute physiology score \>13
•5\. General anesthetic, drug overdose, or alcohol intoxication within the preceding 24 h