Sleep quality in critically ill patients on proportional assist ventilation with load-adjustable gain factors (PAV+) vs pressure support (PS) - a randomised controlled cross-over trial

Cretan Critical Care Society (Greece)0 个研究点目标入组 10 人开始时间: 2009年11月11日最近更新: 2015年1月13日

适应症

试验速览

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•Critically ill patients (>18 years old, both males and females) who are receiving mechanical ventilation for at least 48 hours will be studied. At the time of the study all patients will be haemodynamically stable and ventilated on PS through cuffed endotracheal or tracheostomy tubes with anticipated further mechanical ventilation of at least 24-h duration. All patients must achieve a score of 0 on the Richmond Agitation Sedation Scale (RASS) either with or without intravenous (IV) propofol.

•1. Anticipated ICU stay <24 h
•2. Premorbid diseases that could confuse interpretation of sleep monitoring including central nervous system (CNS) diseases and sleep disorders
•3. Haemodynamic instability (BP <90 mmHg despite therapy)
•4. Glasgow Coma Scale <11 and acute physiology score >13
•5. General anesthetic, drug overdose, or alcohol intoxication within the preceding 24 h

发起方

Cretan Critical Care Society (Greece)