Effects of Female Sex Hormones over the Course of the Menstrual Cycle on Optimal CPAP Pressures Used in the Treatment of Obstructive Sleep Apnoea
Not Applicable
Recruiting
- Conditions
- Obstructive Sleep ApnoeaRespiratory - Sleep apnoea
- Registration Number
- ACTRN12606000461594
- Lead Sponsor
- Institute for Breathing and Sleep
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 20
Inclusion Criteria
Pre-menopausal.
Exclusion Criteria
Other sleep disorderMenstrual cycle disorderTreatment with oral hormone replacementSevere medical, psychological or psychiatric co-morbidities.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Observing any changes in CPAP pressure requirement over five weeks (one menstrual cycle). Estimated that this will occur during the early Luteal phase of the menstrual cycle. The Luteal phase is defined as the period of time following the mid-cycle surge in Luteinising Hormone, and is associated with ovulation. The Luteal phase ends at the beginning of the following menses (menstrual period).[Over five weeks (one menstrual cycle).]
- Secondary Outcome Measures
Name Time Method Patients will be required to note any changes in their normal daily activities as well as medication and alcohol or caffeine intake, in a daily journal supplied by the investigators for 5 weeks, to evaluate if there are any confounding factors that would affect airway patency, sleep quality or core body temperature.[]