Premolar Autotransplantation in Juvenile Dentition: Quantitative Assessment of Vertical Bone and Soft Tissue Growth

Completed

• Conditions: Tooth Aplasia; Traumatic Dental Injury

• Registration Number: NCT02740907
• Lead Sponsor: MKG-Praxisklinik

Brief Summary

Objective:

Premolar autotransplantation represents an effective therapeutic option for the treatment of juvenile dentition in traumatic dental injury with tooth loss. Numerous studies report on the osteoinductive potency of the method, however, to date no quantitative data has been provided. The objective of this prospective clinical study was to quantitatively assess the bone and soft tissue levels after autogenous premolar transplantation by clinical and radiographic parameters.

Materials/Methods:

In the study 26 premolars were transplanted in 20 patients after traumatic dental injury (n=10) or tooth aplasia (n=16) in the upper front. Standard clinical parameters were evaluated. Based on a standardized photo documentation, the relative soft tissue level was measured in comparison to the healthy adjacent teeth. Radiographic findings involved the evaluation of root resorption, pulp canal obliterations and the relative bone height. Patient satisfaction was determined using a standardized questionnaire.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08
• Primary Completion: 2014-10
• Study Completion: 2014-10
• Study First Submitted: 2016-03-22
• Status Verified: 2016-04
• Study First Submitted QC: 2016-04-12
• Last Update Submitted: 2016-04-12
• Study First Posted: 2016-04-15
• Last Update Posted: 2016-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• premolar transplantation after tooth loss in the anterior maxilla (13-23) by aplasia or trauma

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Transplant survival	2006-2014	Evaluation by Kaplan-Meier-Estimator.
Pulp obliteration	2006-2014	Radiographic evaluation.
Sensibility	2006-2014	Assessment of clinical sensibility.
Root resorptions	2006-2014	Radiographic evaluation.
Soft tissue development	2006-2014	Measurement by standardized clinical documentation.
Bone development	2006-2014	Measurement by radiographic evaluation.

Trial Locations

Locations (1)

MKG Praxisklinik; 🇩🇪 Munich, Sauerbruchstraße 48, Germany