Intracardiac T-wave Alternans and Ischemia During Percutaneous Coronary Interventions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
- 主要终点
- Number of Subjects With Positive T Wave Studies During a Coronary Intervention
研究概览
简要总结
T-wave alternans is a test that looks at microvolt changes in the T-wave on a beat to beat basis. The presence or absence of such changes has been shown to predict or exclude future arrhythmic events. The mechanism of T-wave alternans is unclear, but may relate to calcium metabolism in the heart, and may be affected by conditions such as ischemia or heart failure.
The purpose of this study is to determine whether T-wave alternans, as measured through the lead of an implantable defibrillator, is produced by acute ischemia induced by occlusion during percutaneous coronary interventions.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with CAD undergoing PCI with appropriate Medtronic implantable defibrillator.
排除标准
- •non-elective procedure
- •non-qualifying defibrillator type.
结局指标
主要结局
Number of Subjects With Positive T Wave Studies During a Coronary Intervention
时间窗: During the coronary intervention, upto 2 hours
Positive T wave alternans is determined by a proprietary program using ECG recordings during a stress test. The result is reported as positive, negative, or indeterminate.
次要结局
未报告次要终点
研究者
Jose M. Dizon
Assoc Professor of Clinical, Department of Medicine Cardiology
Columbia University