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Peer to Peer Mentoring For Individuals With Early Inflammatory Arthritis: An Effectiveness Study (Pilot RCT)- Peer Mentoring Program

Not Applicable
Completed
Conditions
Early Inflammatory Arthritis
Interventions
Behavioral: Standard of care
Behavioral: One-on-one peer support
Registration Number
NCT01347359
Lead Sponsor
Sunnybrook Health Sciences Centre
Brief Summary

Peer support (including informational, emotional, appraisal support) has been shown to help persons with chronic conditions. The goal of this research is to examine the impact of early peer support on the health and quality of life of individuals with early inflammatory arthritis (EIA). The investigators hypothesize that early peer support will result in improved use of disease modifying anti-rheumatic drug (DMARD) or biologic treatment, self-efficacy, coping efficacy, social support, health-related quality of life, self-management, and disease activity score as well as reduced anxiety for individuals with EIA within two years of their diagnosis. In this study, persons with IA will be trained as peer mentors using a training program developed for a pilot study. Individuals with EIA will be randomized to receive either "peer support program" or "standard care". Peer mentors will be paired with a person with EIA to provide one-on-one support (face-to-face or telephone) once a week for approximately 30 minutes over a 12-week period. All "standard care" participants will receive the peer mentoring intervention at the end of study. Both groups will be evaluated using self-administered questionnaires and clinical assessments, and results of the two groups will be compared. This information will be used to design a larger study.

Detailed Description

Background: The investigators are proposing to examine the effectiveness of a peer support program, the aim of which is to assist individuals with early inflammatory arthritis (EIA) to receive the education and support they need to make decisions to manage their disease. Peer support (including informational, emotional, appraisal support) has been shown to assist persons with chronic conditions and may address challenges with receiving timely and proper treatment in persons with EIA.

Purpose: The goal of this pilot randomized controlled trial (RCT) is to evaluate the effectiveness of peer support to improve the health and quality of life of individuals with EIA. The investigators hypothesize that early peer support will result in improved use of treatment, self-efficacy, coping efficacy, social support, health-related quality of life, self-management, and disease activity score, as well as reduced anxiety for individuals with EIA within two years of their diagnosis.

Methods: This proposal builds on a pilot study, currently underway, to develop and evaluate the acceptability and feasibility of a peer support intervention for persons with EIA. The proposed effectiveness study will employ a RCT design with a wait list control group. Individuals with IA (diagnosis 2 or more years) will be trained as peer mentors using the revised pilot study training program. Peer mentors will be matched with a person newly diagnosed with IA to provide one-on-one support (face-to-face or telephone) over a 12-week period. Individuals with EIA will be recruited from rheumatology clinics at Sunnybrook Health Sciences Centre and Mount Sinai Hospital. Individuals with EIA will be randomized to either "intervention" or "standard care" (wait list). All "standard care" participants with EIA will receive the peer mentoring program at the end of study period; their outcomes will be also be evaluated. Both "intervention" and "standard care" participants will complete clinical assessments and self-administered questionnaires before and after (immediate post-program and 3-month follow-up) study completion to evaluate use of treatment, self-efficacy, coping efficacy, social support, health-related quality of life, anxiety, self-management, and disease activity count.

Implication: The study aims to improve the education and support for patients with EIA. The data from this study will be used to further refine the intervention and study design to be subsequently submitted for further effectiveness testing in a larger scale RCT.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria
  • EIA disease (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis) duration 6 - 52 weeks
  • At least 3 swollen joints, assessed by the treating rheumatologist, OR Positive compression test for the metacarpophalangeal joints, OR Positive compression test for the metatarsophalangeal joints, OR At least 30 minutes of morning stiffness (Lineker et al., 1999)
  • Prescription of a DMARD/biologic by the treating rheumatologist
  • Ability to speak, understand, read and write English without the aid of a secondary support person
  • Ability to provide informed consent
Exclusion Criteria

• Diagnosis of osteoarthritis, Systemic lupus erythematosus, DM neuropathy or trauma

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Control - Standard of careStandard of care"Standard of care" is at the discretion of the treating rheumatologist.
One-on-one peer supportOne-on-one peer supportThe peer support intervention will take the form of a one-on-one peer mentoring program, either face-to-face or by telephone.
Primary Outcome Measures
NameTimeMethod
Use of orally administered DMARD or biologic treatment0 months (baseline), immediate post-program, 3 months post-program

Use of orally administered DMARD or biologic treatment in individuals with EIA as determined indirectly through the modified Morisky scale for medication adherence

Secondary Outcome Measures
NameTimeMethod
Self-efficacy0 months (baseline), immediate post-program, 3 months post-program

Self-efficacy using Self-Efficacy for Managing Chronic Disease 6-Item Scale (SES)

Health-related quality of life0 months (baseline), immediate post-program, 3 months post-program

Health-related quality of life as measured by the Arthritis Impact Measurement Scales, 2nd edition (AIMS2

Social support0 months (baseline), immediate post-program, 3 months post-program

Social support as measured by Medical Outcomes Study Social Support Survey (MOSSS)

Disease activity0 months (baseline), immediate post-program, 3 months post-program

Disease activity as assessed using the Clinical Disease Activity Index (CDAI): A rheumatologist from the research team will conduct clinical assessments for CDAI score, which is a propensity score for disease activity in rheumatoid arthritis. It accounts for upper extremity tender and swollen joints, and patient and evaluator impressions of disease progression

Anxiety0 months (baseline), immediate post-program, 3 months post-program

Anxiety is measured by the Arthritis Impact Measurement Scales, 2nd edition (AIMS2), dimension sub score for anxiety

Coping-efficacy0 months (baseline), immediate post-program, 3 months post-program

Coping-efficacy as assessed using a measure developed by Gignac et al. (2000)

Self-management0 months (baseline), immediate post-program, 3 months post-program

Self-management as evaluated using Patient Activation Measure (PAM) to measure the knowledge, skills, and confidence aspects of self management

Trial Locations

Locations (2)

Mount Sinai Hospital

🇨🇦

Toronto, Ontario, Canada

Sunnybrook Health Sciences Centre

🇨🇦

Toronto, Ontario, Canada

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