Effect of combination therapy with DPP-4 inhibitor and omega 3-fatty acid on glycemic control in type2 diabetes with dyslipidemia

Not Applicable

• Conditions: Type 2 diabetes mellitus

• Registration Number: JPRN-UMIN000010397
• Lead Sponsor: Yokohama City University Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-02
• Study Completion: 2016-01-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

1)severe ketosis, diabetic coma within 6 months 2)present or history of CHF 3)severe infection, before operation, severe trauma 4)severe hepatic dysfunction 5)or severe renal dysfunction (SCr:more than 2.0mg/dl or eGFR less than 30) 6)pregnacy 7)Allergy for DPP-4 inhibitores or omega 3 fatty acid 8)Patients judged by the investigator to be ineligible for some other reason 9)Changes of doses with oral hypoglycemic agents or antihyperelipidemic drugs during the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction rate of postprandial glucose and HbA1c after add-on therapy with omega 3-fatty acid

Secondary Outcome Measures

Name	Time	Method
1)Lipid parameters(TC,LDL-C, HDL-C, TG,etc) 2)Renal function (ACR, Cr, eGFR)