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Clinical Evaluation of Ksheervidari and Bhumyamlaki in Essential Hypertensio

Phase 2
Conditions
Health Condition 1: I10- Essential (primary) hypertension
Registration Number
CTRI/2021/02/031555
Lead Sponsor
Abhishek Upadhyay
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

i.Subjects willing to participate in this clinical trial.

ii.Patients of either sex in the age group 18-70years.

iii.Patients with Stage I Hypertension as per JNC-7 classificationi.e. Systolic blood pressure (SBP) in the range of 140-159 mm of Hg and/or Diastolic blood pressure (DBP) ranging between 90-99 mm of Hg will be included in the study.

Exclusion Criteria

i.Patient not willing to sign the consent form.

ii.Patients below 18 years and above 70 years of age.

iii.Patientswith Stage II Hypertension.

iv.Patients with Secondary Hypertension.

v.Patients taking any antihypertensive medication or who have taken any antihypertensive medication within previous one month.

vi.Patients having any serious illness like Coronary Artery Disease,Cerebrovascular disease, Insulin dependent Diabetes mellitus,Malignancy, etc.

vii.Patients with significant ventricular tachycardia, atrial fibrillation, atrial flutter or other significant arrhythmia.

viii.Patients with any Endocrinal disorders, Renaldisorder or Hepatic disorders.

ix.Patients taking drugs like corticosteroids, oral contraceptives, NSAIDs etc. which may influence the outcome of the study.

x.Patients who show any hypersensitivity towards the trial drugs.

xi.Pregnant and Lactating mothers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Reduction in Systolic and diastolic blood pressureTimepoint: Day 0, 15, 30, 45, 60
Secondary Outcome Measures
NameTimeMethod
Improvement in subjective symptoms of Raktapradoshaj vikara ï??Akshiraga(Redness in eyes) <br/ ><br>ï??Raktapitta(Nasal Bleeding) <br/ ><br>ï??Santapa(Burning sensation) <br/ ><br>ï??Daurbalya(Weakness) <br/ ><br>ï??Shirashoola(Headache) <br/ ><br>ï??Tikta-amlodgara(Sour& bitter eructations) <br/ ><br>ï??Klama(Easy fatigability) <br/ ><br>ï??Krodhaprachurta(Irritability) <br/ ><br>ï??Budhisamoha(Impaired perception) <br/ ><br>ï??Tandra(Drowsiness) <br/ ><br>ï??Nidratiyoga(Excessive Sleep) <br/ ><br>ï??Tamadarshan(Blackouts) <br/ ><br>ï??Mada(Dizziness) <br/ ><br>ï??Kampa(Palpitations) <br/ ><br>Timepoint: 60 days
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