Effects of Metformin on Japanese type 2 diabetes patients: a retrospective study: METRO study
- Conditions
- Type 2 diabetes
- Registration Number
- JPRN-UMIN000040854
- Lead Sponsor
- Yokohama City University Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Not provided
1)Patients with type 1 diabetes or secondary diabetes. 2)Patients whose other diabetes drugs are changed, increased, or discontinued at the same time as the start of metformin administration. 3) Patients who are changing diabetes drugs other than metformin (including changing the dose) during the 24-week observation period (changes in the number of insulin units can be incorporated). 4) Patients who are judged to have extremely poor medication compliance based on medical records. 5) Patients with steroid (oral/injection) treatment. 6) Patients with cancer (can be included if they are in follow-up during remission). 7) Patients who were hospitalized during the observation period. 8) Patients with severe infections and trauma. 9) Patients who are judged to be inappropriate as a subject by the doctor's judgment.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change in HbA1c decrease due to differences in metformin introduction timing (1st, 2nd, 3rd, 4th and later).
- Secondary Outcome Measures
Name Time Method We compare the changes in body weight, biochemical examination, and incidence of adverse events at the time of introduction and at 24 weeks with the difference in the timing of Metformin introduction.