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Pilot study of WT1 peptide vaccine therapy for chemorefractory advanced pancreatic cancer

Not Applicable
Conditions
Pancreatic cancer
Registration Number
JPRN-UMIN000001515
Lead Sponsor
Tohoku University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
10
Inclusion Criteria

Not provided

Exclusion Criteria

1) Patients with uncontrollable infection including active tuberculosis. 2) Patients with severe concurrent disease including malignant hypertension, congestive heart failure, severe coronary disorder, myocardial infarction within 3 months, severe liver cirrhosis, uncontrollable diabetes mellitus, lung fibrosis, interstitial pneumonia, prominent peripheral edeme. 3) Patients who showed severe complication (Grade 3 or more severe according to CTCAE version 3.0) with prior chemotherapy. 4) Patients who require 24 h or more intravenous, transcatheteric nutrition or total parenteral nutrition due to GI symptom. 5) Patients with double cancer. 6) Patients with myelo-dysplastic syndrome or myeopoliferative disease. 7) Pregnant or supposed to be pregnant patient. 8) Patients with past history of severe drug allergy. 9) Patients with severe mental disorder. 10) Patients who is not recommended by attending physician, or trial conductor.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Safty and toxicity Tumor response (Disease control)
Secondary Outcome Measures
NameTimeMethod
Immune response
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