Thiamine Status in Patients with chronic migraine: a case-control study.

Research Cell Sumandeep Vidyapeeth0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

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•70 consecutive adult patients ( > 18 years) of chronic migraine
•70 consecutive adult patients ( > 18 years) of episodic migraine
•70 controls matching for sex, age, education, and socioeconomic status.
•Criteria of episodic migraine
•A. At least five attacks1 fulfilling criteria Bâ??D
•B. Headache attacks lasting 4â??72 hours (when untreated or unsuccessfully treated)
•C. Headache has at least two of the following four characteristics:
•1. unilateral location
•2. pulsating quality
•3. moderate or severe pain intensity
•4. aggravation by or causing avoidance of routine physical activity (e.g. walking or climbing
•D. During headache at least one of the following:
•1. nausea and/or vomiting
•2. photophobia and phonophobia
•E. Not better accounted for by another ICHD-3 diagnosis
•Criteria of chronic migraine
•A. Headache (migraine-like or tension-type-like1) mor3 15 days/month for >3 months, and fulfilling criteria
•B. Occurring in a patient who has had at least five attacks fulfilling criteria Bâ??D for 1.1 Migraine without aura and/or criteria B and C for 1.2 Migraine with aura
•C. On more than 8 days/month for >3 months, fulfilling any of the following:
•1. criteria C and D for 1.1 Migraine without aura
•2. criteria B and C for 1.2 Migraine with aura
•3. believed by the patient to be migraine at onset and relieved by a triptan or ergot derivative
•D. Not better accounted for by another ICHD-3 diagnosis.

•(i)age <18 years;
•(ii)The person who are not willing to take part in the study.
•(iii)Patients who have taken thiamine supplements in the previous 7 days.
•(iv) patients having a history of any acute or chronic disorders (including diabetes mellitus, hypertension, thyroid disorders, epilepsy, Parkinsonâ??s disease, Alzheimerâ??s disease, stroke, brain tumors, palsy of any limb, etc)

发起方

Research Cell Sumandeep Vidyapeeth