EUCTR2007-007864-63-DE进行中（未招募）1 期
Prospective, randomized and controlled clinical trial comparing i.v. bolus application of Abciximab to i.c.application of Abciximab during primary PCU in patients with acute ST-elevation myocardial infarction - Abciximab-STEMI
niversity of Leipzig0 个研究点目标入组 2,065 人开始时间: 2008年2月8日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 2,065
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1) >= 18 years of age
- •2) ST-elevation myocardial infarction, characterized by:
- •a)Clinical symptoms:
- •Angina pectoris < 12 hours and
- •Persistent angina > 30 minutes
- •b) ECG-criteria in 12-lead ECG:
- •ST-segment elevation > 1mm in = 2 extremity leads and / or
- •ST-segment elevation > 2mm in = 2 adjacent precordial leads
- •3) written informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1)Known drug hypersensitivity to Abciximab, other components of the trial medication or murine monoclonal antibodies
- •2)Known drug hypersensitivity to ASS or heparin
- •3)Active peptic ulcus ventriculi or duodeni
- •4)Major surgical interventions, lithotripsy, intracranial / intraspinal interventions or puncture of a not sufficiently compressible vessel less than eight weeks before start of trial
- •5)Intracranial tumors
- •6)Active internal bleeding
- •7)Cerebrovascular complications less than 2 years befor start of trial
- •8)Known coagulation defect or thrombocytopenia
- •9)Arteriovenous malformations or aneurysm
- •10)Severe liver or renal insufficiency (creatinin clearence < 30 ml/min)
- •11)Uncontrolled hypertension, hypertensive retinopathy
- •12)Vasculitis
- •13)Previous thrombolysis (less than 12 hrs ago)
- •14)Lacking compliance
- •15) Pregnant or nursing women
- •16) Fertile female patients (< 2 years post their last menstruation) without using appropriate contraception (i.e. less than 1% per year) when used consistently and correctly such as implants, injectables, combined oral contraceptives, some IUDs, sexual abstinence or vasectomised partner) during trial participation
- •17)Participation in another interventional trial
- •Additional exclusion criteria for the MRT substudy:
- •1) Severe claustrophobia
- •2) Hemodynamic instability
- •3) Pacemaker or internal cardioverter defibrillator (ICD)
- •4) Metallic cerebral or intracranial implants
- •5) Known frug hypersensitivity to Gadolinium
研究者
相似试验
招募中
1 期
Prospective, randomized, clinical, controlled study to investigate the wear behavior and color change of printed composite restorationsWear behavior of composite restorationsColor change of composite restorationsDRKS00024738Charité - Universitätsmedizin BerlinCentrum 3 für Zahn-, Mund- und Kieferheilkunde, Abteilung für Zahnärztliche Prothetik, Alterszahnmedizin und Funktionslehre250
尚未招募
不适用
Prospective, randomized, clinical, controlled study to investigate the wear behavior of different prosthetic materials of single crowns.Abrasion of artificial dental crowns in comparisonthree different crown materials are testedOral health-related quality of life may be affected by prosthetic treatment.DRKS00024377Charité-Universitätsmedizin Berlin, Abteilung für Zahnärztliche Prothetik, Alterszahnmedizin und Funktionslehre69
招募中
不适用
Clinical, prospective, randomised and controlled multicentric split-mouth study to evaluate the healing of an extraction socket with and without autologous, xenogenic or alloplastic bone substitute materialalveolar ridge atrophieK08.2Atrophy of edentulous alveolar ridgeDRKS00026275Klinik- fur Mund-, Kiefer- und Gesichtschirurgie30
招募中
3 期
Comparison of the wound protection ability of Absorbable Collagen Wound Dressings and its impact on wound healing and post-operative pain with sutures.CTRI/2024/06/068753Dr Snehal Pudke
尚未招募
2 期
To identify the benefits of supplementation of vitamin D under supervision as compared to self administration among vitamin D deficient staff working in anesthesia departmentCTRI/2020/01/023087fluid research fund