Isosorbide Mononitrate and Misoprostol in Induction of Labour
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- the number of women who will be reach active phase within 24 hours
研究概览
简要总结
Induction of labor is defined as the process of artificially initiating uterine contractions, prior to their spontaneous onset, with progressive effacement and dilatation of the cervix and ultimately, the delivery of the baby.
详细描述
There are many indications for induction of labor in the obstetric practice, of which prolonged gestational age stands as the most common cause.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 42 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Single vertex presentation.
- •Gestational age > 37weeks calculated from last menstrual period or U/S scanning.
排除标准
- •Patients with rupture of membranes.
- •Previous uterine scar.
- •Fetal malpresentation.
- •Multiple pregnancies.
研究组 & 干预措施
women receiving isosorbide mononitrates lower dose
women who will receive isosorbide mononitrates lower dose
干预措施: Isosorbide Mononitrate 40 MG (Drug)
women receiving isosorbide mononitrates higher dose
women who will receive isosorbide mononitrates higher dose
干预措施: Isosorbide Mononitrate 60 MG (Drug)
Women receiving misoprostol
Women who will receive misoprostol
干预措施: Misoprostol (Drug)
结局指标
主要结局
the number of women who will be reach active phase within 24 hours
时间窗: 24 hours
how many women will reach active phase within 24 hours
次要结局
未报告次要终点