A comparative clinical trial to study the effects of two ayurvedic medicines, simple distillation of plant Prishniparni and Chitraka haritaki rasayana along modern treatment in patients of Chronic Heart Failure.
- Conditions
- Health Condition 1: I501- Left ventricular failure, unspecified
- Registration Number
- CTRI/2024/03/064622
- Lead Sponsor
- All India Institute of Ayurveda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Age: above 21 years and below 60years.
2.Gender: both male and female
3.Diagnosed case of CHF: NYHA function classification II - III/ Stage C HF – according to AHA
4.LVEF <30 % - measured by a two-dimensional echocardiogram.
5.Raised Pro-BNP (above normal for the given age)
6.Willingness for participation in the study
1.Primary organic valvular disease and severe CAD needs surgical intervention.
2.Pulmonary hypertension (PAP > 25mmHg)
3.History of CABG - PTCA - PCI or any other cardiac surgical intervention.
4.Patients having active infective cardiac disease
5.Any evidence of thrombo-embolic heart disease or peripheral arterial disease (Ankle-Brachial index >1.4)
6.Any history of CVA - TIA - DVT or pulmonary embolism in the past 6 months.
7.Pregnant or lactating women.
8.non-willingness to take Ayurvedic medicine.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method •Changes in Cardiac Biomarker & Ventricular Ejection Fraction <br/ ><br>Timepoint: day 1 day 75
- Secondary Outcome Measures
Name Time Method •Exercise tolerance capacity (6minute walking distance change - 6MWT) <br/ ><br>•Changes in Cardiac Function Grading (New York Cardiac Function Grading NYHA) <br/ ><br>•Changes in health-related quality of life (CHF related quality of life) <br/ ><br>Timepoint: day 1 <br/ ><br>day 15 <br/ ><br>day 30 <br/ ><br>day 45 <br/ ><br>day 60 <br/ ><br>day 75