Effect of Hp Infection on the Quality of Gastric Mucosa Preparation

Recruiting

• Conditions: Helicobacter Pylori Infection

• Registration Number: NCT05527496
• Lead Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University

Brief Summary

The purpose of this study was to evaluate the effect of Helicobacter pylori infection on the quality of gastric mucosa preparation.

Detailed Description

The purpose of this study was to evaluate the effect of Helicobacter pylori infection on the quality of gastric mucosa preparation by comparing the cleanliness of gastric mucosa between patients with Helicobacter pylori infection and those without Helicobacter pylori infection.

Study Timeline

• Study Start: 2022-08-01
• Study First Submitted: 2022-08-31
• Status Verified: 2022-09
• Study First Submitted QC: 2022-09-01
• Last Update Submitted: 2022-09-01
• Study First Posted: 2022-09-02
• Last Update Posted: 2022-09-02
• Primary Completion: 2023-08-01
• Study Completion: 2023-08-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Adults who volunteered to participate in this study and signed an informed consent form
• Have been tested for Helicobacter pylori and have definite test results

Exclusion Criteria

• Contraindications for gastroscopy (such as severe cardiopulmonary diseases, liver and kidney dysfunction, shock, etc.)
• History of upper gastrointestinal surgery
• Therapeutic endoscopy and emergency surgery are required
• Recent history of upper gastrointestinal bleeding
• Corrosive substance ingestion
• The pregnancy
• Abnormal mental state cannot cooperate with the examination
• Patients with contraindications to the drugs used in the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cleanliness of gastric mucosa	The time the patient underwent gastroscopy procedure	The visibility of gastric mucosa was scored for four parts of the stomach (antrum, upper body, lower body and fundus).

Secondary Outcome Measures

Name	Time	Method
Time to complete gastroscopy	The day of gastroscopy	The time from the start of the endoscopy to the complete removal of the endoscope
Patient comfort score	Records were made on the 1 day of the gastroscopy	Prior to endoscopy, the patient was instructed to indicate the level of discomfort on a visual analogue scale, which was rated by the patient on a scale of 0 to 10, with 0 indicating no discomfort and 10 indicating maximum discomfort.
adverse reaction	Within 24 hours after endoscopy	Adverse reactions to study drugs, and respiratory, cardiovascular, or endoscopic adverse events.
Endoscopic findings	About 15 days after endoscopy	The diagnostic results were recorded under gastroscopy, and if the biopsy was taken under gastroscopy, the pathological results were also recorded

Trial Locations

Locations (1)

The Second Affiliated Hospital of Xi 'an Jiaotong University; 🇨🇳 Xi'an, Shaanxi, China