Opportunities and Limits to Deprescribing in Nursing Homes: Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 62
- 试验地点
- 2
- 主要终点
- Number of Inappropriate Medication at Follow-up
研究概览
简要总结
This study will evaluate the effects of a pharmacist-led, deprescribing-focused medication review on the use of inappropriate medications by nursing home residents
详细描述
Nursing home residents are often prescribed inappropriate medication, drugs whose negative effects outweigh potential benefits or which are not useful anymore. Inappropriate medication have been linked with worse health outcomes, hospitalisations and death. Deprescribing, the structured process of withdrawing or tapering inappropriate medications, has been studied as a potential solution to this problem.
In this study, nursing home residents living in institution which are already engaged in a deprescribing process will be randomly allocated to receive a medication review or usual care. The medication review will be performed by the nursing home pharmacist an its results will be discussed with the responsible physicians and nurses to create a deprescribing plan specifically tailored to the needs of the resident.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Take 5 or more prescribed drugs daily;
- •Reside in the Nursing Home since at least 4 months.
排除标准
- •Physician judges that discussing deprescribing with them risks destabilising them.
结局指标
主要结局
Number of Inappropriate Medication at Follow-up
时间窗: 4 months
Number of inappropriate medications prescribed at follow-up, assessed using the French translation of STOPP v2.
次要结局
- Number of Chronic DDDs Prescribed to Participants(4 months)
- Number of Common Drug-related Complaints at Follow-up(4 months)
- Number of Potentially Inappropriate DDDs Prescribed to Participants at Follow-up(4 months)
- Number of New Drugs Prescribed as a Result of the Intervention(4 months)
- Number of Chronic Drugs Prescribed to Participants(4 months)
- Health-related Quality of Life(4 months)
研究者
Anne Niquille
Doctor
University of Geneva, Switzerland