Prospective evaluation to test the effectiveness of the BlephEx® procedure for eyelid margin care in patients with blepharitis and dry eye
Not Applicable
- Conditions
- Blepharitis
- Registration Number
- DRKS00033492
- Lead Sponsor
- Klinik für Augenheilkunde, Universitätsklinikum Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
symptomatic blepharitis (at least Grade 2 according to the Efron grading scale), age older than 18 years, decimal visual acuity >0.5, blepharitis refractory to eyelid margin care and the use of lubricating drops for at least 4 weeks
Exclusion Criteria
routine (daily) contact lens wear, other eyelid or ocular surface diseases, previous ocular surgery, previous treatment with cyclosporin A or steroids, pregnancy, autoimmune diseases (e.g. Sjögren's syndrome, endocrine orbitopathy) or other immunological diseases and acute infections. Further exclusion criteria were the presence of trachoma, atopic dermatitis, diabetes mellitus, severe systemic diseases, graft-versus-host disease or the use of antibiotics in the last 4 weeks
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survey using a standardized questionnaire on dry eye (OSDI)
- Secondary Outcome Measures
Name Time Method Tear film break-up time; Efron Grading Scale: grading of blepharitis at the eyelid margin