The tolerance to RISA root canal irrigation fluid determined in an in-vivo study - TIGRIS

Academisch Centrum Tandheelkunde Amsterdam (ACTA)0 个研究点目标入组 18 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•- apical periodontitis has been diagnosed and confirmed with an intra-oral radiograph and appears on the radiograph as a radiolucent area around one or more root tips of the affected tooth. A root canal treatment has a reasonable/good prognosis (Sjögren et al. 1990) and the subject prefers NSRCT over tooth extraction or monitoring. The affected tooth has not previously received a complete root canal treatment.
•- no spontaneous pre-operative pain or spontaneous pre-operative pain less than 36
•- no or mild swelling
•- if present, draining or no-draining sinus tract
•- 18 - 75 years.
•- completed the medical history questionnaire.
•- all teeth except third molars
•- DPSI of subject tooth is <=3-
•- tooth mobility <=1
•- signed the informed consent form

•Subject tooth related criteria:
•- third molar
•- pain >36 on Heft-Parker VAS scale (fig. 1)
•- subject tooth with a mobility score 2 or more
•- subject tooth with a periodontal pocket depth DPSI >=3+
•- subject tooth with open or incompletely formed root apices
•- subject tooth that requires a post
•- subject tooth with a vertical fracture or horizontal fracture extending below the cemento-enamel junction of the tooth
•- teeth in the same quadrant requiring root canal therapy
•- teeth with hypersensitive dentine in the same left or right facial half
•- absence of periapical radiolucency in the presence of tenderness to percussion.
•- absence of periapical radiolucency in the absence of pulp sensitivity
•- previous completed (non)surgical (root-canal) treatment on subject tooth
•- severe swelling originating from affected tooth;Current medication related criteria:
•- chronic use of pain relief medication
•- (par)enteral use of bisphosphonates
•- systemic corticoid therapy;General-health related criteria:
•- non-odontogenic facial pain
•- any known infectious diseases (eg, human immunodeficiency virus, hepatitis B, hepatitis C, tuberculosis, or prion induced disease)
•- history of cancer in the oral-maxillofacial region
•- history of cancer in the last two years
•- history of head and/or neck radiation therapy
•- diabetes mellitus type I,
•- chronic inflammatory diseases like morbus Crohn or rheumatoid arthritis

发起方

Academisch Centrum Tandheelkunde Amsterdam (ACTA)