Assessment of Ovarian Reserve Tests in Unexplained Infertile Women

Completed

• Conditions: Infertility; Infertility, Female

• Registration Number: NCT02127944
• Lead Sponsor: Karadeniz Technical University

Brief Summary

IN UNEXPLAINED INFERTILITY IN WOMEN ,OVARY RESERVE IS BORDERLINE IF ASSESSED USING HIGH-SENSITIVE TESTS.

Detailed Description

IN UNEXPLAINED INFERTILITY OVARIAN RESERVE TESTS WERE ASSESSED.

IN THIS STUDY, A COMPARISON IS DONE BETWEEN 35 WOMEN WITH UNEXPLAINED FERTILITY(THE PATIENT) AND 35 WOMEN WHO DON'T HAVE ANY FERTILITY PROBLEMS AND HAVE AT LEAST A CHILD (THE CONTROL GROUP).

THE STUDY PARTICIPANTS SHOULD HAVE THE FOLLOWING CRITERIA

Inclusion Criteria:

LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES SHOULD HAVE AT LEAST A YEAR OF UNPROTECTED SEX. THE HUSBAND'S SPERMOGRAM SHOULD HAVE NO ABNORMALITIES THE SUBJECT SHOULD HAVE A NORMAL HYSTEROSALPHINGOGRAPHY

Exclusion Criteria:

HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE.

FOR THE CONTROL GROUP

Inclusion Criteria:

LESS THAN 35 YEARS OLD, MARRIED WOMEN SHOULD HAVE REGULAR MENSES AT LEAST HAVE A CHILD THE HUSBAND'S SPERMOGRAM SHOULD HAVE NO ABNORMALITIES THE SUBJECT SHOULD HAVE A NORMAL HYSTEROSALPHINGOGRAPHY

Exclusion Criteria:

HAVING ANY SYSTEMIC DISEASE. LONG HISTORY OF ANY DRUG USAGE.

THE STUDY INCLUDES THE FOLLOWING TESTS BEING DONE ON THE PATIENTS:

THE FOLLOWING HORMONES' LEVELS WERE STUDIED:AMH (ANTI-MULLERIAN HORMONE),FSH (FOLLICULAR STIMULATING HORMONE) , E2 (ESTRADIOL) AND INHIBIN B.THE FORMER THREE HORMONE LEVELS SHOULD BE ASSESSED ON THE THIRD DAY OF MENSES IN THE STUDY,TRANSVAGINAL ULTRASONOGRAPHIC OVARIAN VOLUME ,OVARIAN ANTRAL FOLLICULE NUMBER,OVARIAN STROMAL BLOODFLOW AND OVARIAN ARTERIAL RESISTANCE WAS MEASURED USING DOPPLER ULTRASONOGRAM.

Study Timeline

• Study Start: 2014-04
• Study First Submitted: 2014-04-15
• Study First Submitted QC: 2014-04-28
• Study First Posted: 2014-05-01
• Primary Completion: 2015-06
• Study Completion: 2015-07
• Status Verified: 2018-12
• Last Update Submitted: 2018-12-06
• Last Update Posted: 2018-12-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

• LESS THAN 35 YEARS OLD,
• MARRIED WOMEN
• SHOULD HAVE REGULAR MENSES
• SHOULD HAVE AT LEAST A YEAR OF UNPROTECTED SEX.

Exclusion Criteria

• HAVING ANY SYSTEMIC DISEASE.
• LONG HISTORY OF ANY DRUG USAGE.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
LEVELS OF OVARIAN RESERVE MARKERS IN THE SERUM	ONE DAY	AMH (ANTI-MULLERIAN HORMONE),FSH (FOLLICLE STIMULATING HORMONE),E2 (ESTRADIOL)AND INHIBIN -B LEVELS WILL BE TESTED

Secondary Outcome Measures

Name	Time	Method
ULTRASONOGRAPHIC ASSESSMENT OF OVARIAN RESERVE MARKERS	ONE DAY	OVARIAN ANTRAL FOLLICULE COUNT ,OVARIAN VOLUME MEASUREMENT,OVARIAN DOPPLER -ULTRASONOGRAPHIC ASSESSMENT

Trial Locations

Locations (1)

Ktu Farabi Hospital; 🇹🇷 Trabzon, Turkey