EUCTR2020-000204-11-DK进行中（未招募）1 期
Effect of subcutaneous semaglutide 2.4 mg once-weekly compared to placebo in subjects with obesity and knee osteoarthritis
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 375
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Male or female, age above or equal to 18 years at the time of signing informed consent
- •- Body Mass Index (BMI) greater than or equal to 30.0 kg/m^2
- •- Clinical diagnosis of knee OA (American College of Rheumatology (ACR) criteria) with moderate radiographic changes (Kellgren-Lawrence (KL) grades 2 or 3 as per central reading) in target knee. Target knee joint is defined as most symptomatic knee at screening. If pain in knees are equal target knee joint will be in the most dominant leg.
- •- Pain due to knee OA
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 356
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 19
排除标准
- •- Joint replacement in target knee
- •- Arthroscopy or injections into target knee within last 3 months prior to enrolment
- •- Any other joint disease in the target knee
研究者
相似试验
进行中（未招募）
1 期
Research study looking at how well semaglutide works in people suffering from obesity and knee osteoarthritisMedDRA version: 20.0Level: PTClassification code 10029883Term: ObesitySystem Organ Class: 10027433 - Metabolism and nutrition disordersObesityEUCTR2020-000204-11-FRovo Nordisk A/S375
进行中（未招募）
1 期
Research study looking at how well semaglutide works in people suffering from obesity and knee osteoarthritisMedDRA version: 20.0Level: PTClassification code 10029883Term: ObesitySystem Organ Class: 10027433 - Metabolism and nutrition disordersObesityEUCTR2020-000204-11-NOovo Nordisk A/S375
进行中（未招募）
1 期
Research study looking at how well semaglutide works in people suffering from obesity and knee osteoarthritisMedDRA version: 20.0Level: PTClassification code 10029883Term: ObesitySystem Organ Class: 10027433 - Metabolism and nutrition disordersObesityEUCTR2020-000204-11-SEovo Nordisk A/S375
进行中（未招募）
1 期
Research study looking at how well semaglutide works in people living with obesity and prediabetesMedDRA version: 20.0Level: PTClassification code 10029883Term: ObesitySystem Organ Class: 10027433 - Metabolism and nutrition disordersObesityEUCTR2020-002939-29-FIovo Nordisk A/S201
进行中（未招募）
1 期
Research study looking at how well semaglutide works in people living with obesity and prediabetesMedDRA version: 20.0Level: PTClassification code 10029883Term: ObesitySystem Organ Class: 10027433 - Metabolism and nutrition disordersObesityEUCTR2020-002939-29-DKovo Nordisk A/S201