A randomised controlled trial to evaluate the effect of cognitive training and transcranial direct current stimulation on cognitive function and quality of life in people with Parkinson's disease and mild cognitive impairment

Blake Lawrence0 个研究点目标入组 54 人开始时间: 2014年9月26日最近更新: 2020年1月13日

适应症

试验速览

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•Individuals must meet the following criteria to be eligible to participate in the study: 1) diagnosed with idiopathic Parkinson's Disease by a neurologist or geriatrician in accord with the Unite Kingdom Parkinson's Disease Society Brain Bank Clinical (UKPDSBBC) criteria; 2) describe self-reported problems with cognition which do not significantly impact on functional independence; 3) presence of mild cognitive impairment in accord with the Movement Disorders Society Level II diagnostic criteria; 4) stable response to antiparkinsonian medication for a minimum period of 2 months.

•Individuals will be excluded from the study in they meet the following criteria: 1) presence of Parkinson's Disease-Dementia; 2) below average premorbid intelligence; 3) history of brain surgery; 4) a deep brain stimulation (DBS) implant; 5) history of epilepsy; 6) any active skin disease on the scalp; 7) unstable medical condition (Parkinson’s is not classified as an unstable condition); 8) currently taking psychoactive medication (Parkinson’s medication will not impact TDCS); 9) history of migraine; 10) history of episodes of faintness; 11) history of asthma; 12) any metal implants in the head/brain; 13) currently using a hearing aid.

发起方

Blake Lawrence