Investigation of the effect of artemisinin and Dermaneh and Afsantinin the treatment of coronavirus COVID-19 virus

Phase 3

Conditions: COVID-19.
COVID-19, virus identified
U07.1

Registration Number: IRCT20201027049164N6

Lead Sponsor: Kerman University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 30

Inclusion Criteria

Patients with signing Informed Consent
Age 18-65 years old
Positive CRP test for SARS-CoV-2 virus or characteristic signs on a CT scan of the chest with mild to moderate clinical manifestations according to the National Early Warning Score (NEWS) (mild: 1-4 / moderate: 5-6)

Exclusion Criteria

Receipt of any another experimental treatment
Severe liver disease
Known allergic reaction to drugs
Severe renal disease
Pregnant or breastfeeding women
transfer to the intensive care unit

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxygen saturation. Timepoint: At the beginning (before the intervention) and 14 days after intervention. Method of measurement: Pulse Oximeter.;Respiratory Rate. Timepoint: At the beginning of the study (before the intervention) and14 days after intervention. Method of measurement: Respiratory Count.;C-reactive protein. Timepoint: At the beginning of the study (before the intervention) , 7 days after the intervention, 14 days after intervention. Method of measurement: Venous blood test.;Lymphocytes. Timepoint: At the beginning of the study (before the intervention) and 14 days after intervention. Method of measurement: Venous blood test.

Secondary Outcome Measures

Name	Time	Method
Headache. Timepoint: At the beginning of the study (before the intervention) and 14 days after the intervention. Method of measurement: Questionnaire.;Muscle pain. Timepoint: At the beginning of the study (before the intervention) and 14 days after the intervention. Method of measurement: Questionnaire.;Sore throat. Timepoint: At the beginning of the study (before the intervention) and 14 days after the intervention. Method of measurement: Questionnaire.;Anorexia. Timepoint: At the beginning of the study (before the intervention) and 14 days after the intervention. Method of measurement: Questionnaire.;Fatigue. Timepoint: At the beginning of the study (before the intervention)and 14 days after the intervention. Method of measurement: Questionnaire.;Cough. Timepoint: At the beginning of the study (before the intervention) and 14 days after the intervention. Method of measurement: Questionnaire.