JPRN-jRCT2080221538未知3 期
A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events With Ticagrelor Compared to Placebo on a Background of Acetyl Salicylic Acid (ASA) Therapy in Patients With History of Myocardial Infarction
适应症
试验速览
- 阶段
- 3 期
- 发起方
- AstraZeneca
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 50age old 至 ot applicable（—）
- 性别
- All
入选标准
- •Person who had a heart attack within 1 - 3 years ago and at least one additional risk factor: Age 65 years old or more, Diabetes requiring medication, Documented history of 2nd prior MI (>1 year ago). Angiographic evidence of multivessel CAD, and/or Chronic, non-end stage renal dysfunction.
- •- Females of child-bearing potential must have a negative pregnancy test at enrollment
- •- Persons who are currently taking aspirin between 75 and 150 mg once daily
排除标准
- •- Persons who are being treated with agents inhibiting blood clotting if the agent cannot be stopped at study start
- •- Persons who have planned coronary, cerebrovascular, or peripheral arterial Revascularization (invasive surgery) at study start
- •- Person with known bleeding disorders
- •- Persons who need chronic oral anticoagulant therapy or chronic low-molecular-weight heparin
- •- Persons with a history of ischemic stroke
- •- Persons with a history of intracranial bleeding at any time, a tumor or blood vessel abnormality in the brain and/or spinal cord at any time, a history of surgery involving the brain or spinal cord within the last 5 years, or a history of bleeding from the gastrointestinal tract (eg, esophagus, stomach, colon, rectum) within the last 6 months or a major surgery within the last 30 days.
- •- Persons considered to be at risk of bradycardic events unless already treated with a permanent pacemaker
- •- Persons who have had open heart surgery within the past 5 years, unless the person had a heart attack after the surgery
- •- Person with known severe liver disease
- •- Persons with kidney failure requiring dialysis
- •- Persons with life expectancy < 1 year
研究者
相似试验
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Prevention of cardiovascular events (eg, death from heart or vascular disease, heart attack, or stroke) in patients with prior heart attack using ticagrelor compared to placebo on a background of aspirin.EUCTR2009-017242-30-ROAstraZeneca AB21,162
已完成
3 期
A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events with Ticagrelor Compared to Placebo on a Background of Acetyl Salicylic Acid (ASA) Therapy in Patients with History of Myocardial Infarctioatherothrombotic eventsobstruction of a coronary artery10011082NL-OMON39760Astra Zeneca700
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A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events with Ticagrelor Compared to Placebo on a Background of Acetyl Salicylic Acid (ASA) Therapy in Patients with History of Myocardial Infarction - PEGASUS - TIMI 54Myocardial Infarction, Cardiovascular Death, Atherothombosis, StrokeMedDRA version: 13.1Level: LLTClassification code 10007648Term: Cardiovascular disease, unspecifiedSystem Organ Class: 10007541 - Cardiac disordersEUCTR2009-017242-30-SKAstraZeneca AB21,000
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进行中（未招募）
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A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events with Ticagrelor Compared to Placebo on a Background of Acetyl Salicylic Acid (ASA) Therapy in Patients with History of Myocardial Infarction - PEGUSUSMyocardial Infarction, Cardiovascular Death, Atherothrombosis,strokeMedDRA version: 9.1Level: SOCClassification code 10007541EUCTR2009-017242-30-ITASTRAZENECA21,000