To compare effects of ropivacaine alone and ropivacaine along with nalbuphine and magnesium sulphate in pain control among children in regional anaesthesia(caudal block)
Phase 4
- Conditions
- Health Condition 1: U07-U07- Provisional assignment of new diseases of uncertain etiology or emergency use
- Registration Number
- CTRI/2021/10/037040
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Paediatric participants aged between 1-10 years.
American Society of Anaesthesiologists grade I and
II patients.
Patients undergoing infraumbilical surgeries.
Exclusion Criteria
History of developmental delay or mental retardation, which could make observational pain intensity assessment difficult.
Children with known allergy to any of the study drugs.
Children with coagulation disorders.
Childrenwith coexisting medical illness.
Pre-existing neurological diseases.
Anatomical abnormalities of spine and sacrum.
Any signs of infection at the site of the proposed caudal block.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate analgesic efficacy of ropivacaine alone in paediatric caudal block <br/ ><br>To evaluate analgesic efficacy of ropivacaine with nalbuphine in paediatric caudal block <br/ ><br>To evaluate analgesic efficacy of ropivacaine with magnesium sulphate in paediatric caudal block <br/ ><br>To compare analgesic efficacy of ropivacaine alone ,with nalbuphine and with magnesium sulphate in paediatric caudal block <br/ ><br>Timepoint: Duration of analgesia will be assessed. <br/ ><br>Pain intensity will be assessed at end of operation every 2hrly ,4hrly and 8hrly using FLACC Pain scale. <br/ ><br>
- Secondary Outcome Measures
Name Time Method Monitoring of hemodynamic parameters ( HR,Oxygen saturation ,Temperature) intraoperatively and postoperatively. <br/ ><br>Perioperative adverse effects will be recorded. <br/ ><br>Timepoint: Vitals monitoring will be done before induction and every 5 min for half an hour and every 10 min until the end of surgery <br/ ><br>Postoperative hemodynamic monitoring for 24hrs will be done <br/ ><br>