study to assess efficacy of extended regimen of letrozole in infertile women with polycystic ovarian syndrome

Phase 2

• Conditions: Health Condition 1: N970- Female infertility associated withanovulationHealth Condition 2: E282- Polycystic ovarian syndrome

• Registration Number: CTRI/2023/10/059166
• Lead Sponsor: AIIMS NEW DELHI

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Any patient from 21-38 years attending gynaecology OPD with features of PCOS as per modified Rotterdam criteria i.e. with 2/3 features: Oligo/anovulation, clinical and/or biochemical evidence of hyperandrogenism

Normal husband semen parameters as per sixth edition WHO semen analysis 2021 criteria.

Patient with at least one patent fallopian tube confirmed by hysterosalpingography or laparoscopy.

Patient with controlled thyroid disorders.

Patient with normal prolactin levels.

Patient with no ovarian surgery.

Patient who are not on any hormonal contraception or insulin sensitizers in last 3 months.

Exclusion Criteria

Patients less than 21 years and more than 38 years.

Patient with history of endometriosis.

Patient with diminished ovarian reserve (AMH <1.5 ng/ml, AFC <7, FSH >10 IU/ml).

Patient with uncontrolled thyroid disorder.

Patient with hyperprolactinemia.

Patient with non-classical congenital adrenal hyperplasia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified