Effects of high intensity interval training on exercise capacity in people with cystic fibrosis
- Conditions
- Cystic fibrosis (CF)Respiratory - Other respiratory disorders / diseasesPhysical Medicine / Rehabilitation - PhysiotherapyHuman Genetics and Inherited Disorders - Cystic fibrosis
- Registration Number
- ACTRN12617001271392
- Lead Sponsor
- Institute for Respiratory Health - Conquer Cystic Fibrosis Research Program
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 14
People with CF aged 15 years or older and have a body mass index (BMI) > 16 kg/m2 will be eligible to participate.
(i) A current or recent (within the previous 4 weeks) exacerbation of CF which required oral or intravenous antibiotics; (ii) a co-morbid condition that would impact on the ability to undertake a maximal incremental exercise capacity test; (iii) poorly controlled diabetes as deemed by their treating endocrinologist; (iv) a previous lung transplant or current listing for lung transplantation; (v) individuals who have consistently trained at a moderate intensity 2 or more times per week for the previous 3 months and; (vi) the inability to provide written informed consent due to a cognitive impairment or being unable to understand English.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Exercise endurance (time to symptom limitation during a cycling-based constant work rate test [Tlim]). Time to symptom limitation will be defined as the time it takes from when a participant starts cycling (at 80% of their Wmax on a an ergometer), to when they are unable to continue cycling due to intolerable symptoms of breathlessness or muscle fatigue. [Baseline (pre-randomisation) and follow-up (i.e. following the 8 week intervention) assessment periods ]
- Secondary Outcome Measures
Name Time Method