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Clinical Trials/NCT04229732
NCT04229732
Unknown
Not Applicable

Trials of Ventilation Assisted Substance Elimination Via the Lung - Ethanol (VASEL - Ethanol)

University Health Network, Toronto0 sites40 target enrollmentJuly 2020
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ConditionsAlcohol Intoxication

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Alcohol Intoxication
Sponsor
University Health Network, Toronto
Enrollment
40
Primary Endpoint
Alcohol elimination time constant
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

This prospective, randomized control trial will use passive, isocapnic hyperventilation, applied via the ClearMateTM device (Thornhill Medical, Inc) versus controls receiving standard of care supportive management for severe alcohol intoxication to assess for enhanced ethanol elimination kinetics.

Registry
clinicaltrials.gov
Start Date
July 2020
End Date
July 2022
Last Updated
6 years ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •intoxicated requiring admission to an emergency unit

Exclusion Criteria

  • •Liver or renal disease

Outcomes

Primary Outcomes

Alcohol elimination time constant

Time Frame: 6-24 hours

From the recorded venous ethanol blood alcohol values, an elimination time constant will be calculated

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