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临床试验/NCT00738166
NCT00738166已完成不适用

Content, Bioavailability and Health Effects of Trace Elements and Bioactive Components in Organic Agricultural Systems

University of Copenhagen1 个研究点 分布在 1 个国家目标入组 18 人开始时间: 2007年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
18
试验地点
1
主要终点
Bioavailability of trace elements and secondary metabolites

研究概览

简要总结

Trace elements, bioactive secondary metabolites and vitamins are among the most important quality parameters in plants. Yet, very little information is available on their content, bioavailability and health effects of organically grown plant food products. The main objective of the project is to study the impact of different agricultural management practises relevant for organic farming on the ability of cereal and vegetable crops to absorb trace elements from the soil and to synthesise bioactive compounds (secondary metabolites, antioxidant vitamins and phytates) with health promoting effects. Field experiments with a rigidly controlled design will be implemented together with state-of-the-art analytical techniques allowing solid conclusions to be drawn on the variability and optimum levels of bioactive compounds. The multitude of analytical data from plant and soil samples will be analysed by multivariate statistical methods in order to reveal differences between the cultivation systems used. Finally, the relationship between bioavailability of the nutrients studied and the elemental fingerprint of plants will be extracted by the statistical methods.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Healthy adults aged 18-45 years
  • •BMI 20-30 kg/m2
  • •Non-vegetarian

排除标准

  • •Physical activity > 10 h/week
  • •Intake of dietary supplements
  • •Regular use of drugs
  • •Chronic diseases
  • •Excessive intake of alcohol

研究组 & 干预措施

II

Experimental

organic animal manure

干预措施: Organic or conventional diet (Other)

II

Experimental

organic animal manure

干预措施: Diet (organic or conventional) (Other)

III

Active Comparator

conventional

干预措施: Organic or conventional diet (Other)

III

Active Comparator

conventional

干预措施: Diet (organic or conventional) (Other)

I

Experimental

organic green manure

干预措施: Organic or conventional diet (Other)

I

Experimental

organic green manure

干预措施: Diet (organic or conventional) (Other)

结局指标

主要结局

Bioavailability of trace elements and secondary metabolites

时间窗: 3 x 12 days

次要结局

  • Health factors(3 x 12 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Arne Astrup

Professor

University of Copenhagen

研究点 (1)

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