Dachaihu Decoction Compound and Rhubarb Single Medicine in the Treatment of Acute Pancreatitis

Not Applicable

Not yet recruiting

• Conditions: Acute Pancreatitis
• Interventions: Drug: Rhubarb single medicine; Combination Product: Dachaihu decoction compound; Combination Product: Regular therapies

• Registration Number: NCT04990336
• Lead Sponsor: Fifth Affiliated Hospital, Sun Yat-Sen University

Brief Summary

A large number of clinical studies have shown that oral administration, external application or enema of Chinese medicine can promote the recovery of gastrointestinal function and the absorption of pancreatic inflammation. The aims of the study is to explore the application of Dachaihu Decoction Compound (DDC)and Rhubarb Single Medicine (RSM) in the Treatment of Acute Pancreatitis.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-07
• Study First Submitted: 2021-07-27
• Study First Submitted QC: 2021-07-27
• Study First Posted: 2021-08-04
• Last Update Submitted: 2022-03-22
• Last Update Posted: 2022-03-24
• Study Start: 2023-09-01
• Primary Completion: 2029-01-31
• Study Completion: 2029-07-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 306

Inclusion Criteria

• Age from 18 to 65 years old
• Meet the diagnostic criteria of western medicine for acute pancreatitis, within 48 hours of onset
• Consent of the subjects, who sign the informed consent form

Exclusion Criteria

• Women who are pregnant or breastfeeding
• Acute abdomen such as organic intestinal obstruction, gastrointestinal perforation, purulent cholangitis, etc.
• Patients with a history of severe heart, liver, kidney and other important organ diseases
• Patients with mental illness and malignant tumors
• People who have allergies, or are allergic to a certain drug ingredient

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
DDC(Dachaihu decoction compound) Group	Regular therapies	Treated with Dachaihu decoction compound and regular therapies
RSM(rhubarb single medicine) Group	Rhubarb single medicine	Treated with rhubarb single medicine and regular therapies
DDC(Dachaihu decoction compound) Group	Dachaihu decoction compound	Treated with Dachaihu decoction compound and regular therapies
RSM(rhubarb single medicine) Group	Regular therapies	Treated with rhubarb single medicine and regular therapies
N Group	Regular therapies	Treated with regular therapies and without traditional Chinese medicine

Primary Outcome Measures

Name	Time	Method
Significant and effective rate	7 days	Significant and effective rate after 7 days of treatment