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Clinical Trials/NCT04948775
NCT04948775
Completed
Not Applicable

Effect of Cervical Stabilization Exercises on Cervical Proprioception, Functional Status and Quality of Life in Patients With Rheumatoid Arthritis

Izmir Katip Celebi University1 site in 1 country26 target enrollmentNovember 28, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rheumatoid Arthritis
Sponsor
Izmir Katip Celebi University
Enrollment
26
Locations
1
Primary Endpoint
Change in Cervical Reposition Error
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The aim of this study is to investigate the effectiveness of cervical stabilization exercises on cervical positioning error in rheumatoid arthritis.

Detailed Description

Rheumatoid arthritis (RA) is a chronic, recurrent polyarthritis of the synovial joints. Although the prevalence of the disease shows ethnic differences, the average prevelance of the disease is 1%, and the female/male ratio is 2.5-3/1. The average age of onset is between 30-50 years. Common cervical involvement in RA patients was first described by Garrod in 1890. The most common inflammatory arthritis involving the cervical vertebra is RA. Thoracic and lumbar spine involvement is less common compared to cervical spine involvement in the disease. Proprioceptive sense is defined as a type of specialized sensory model that includes joint movement (kinesthesia) and position sense. Mechanoreceptors located in different structures such as muscle, tendon, joint capsule and skin in both axial joints and peripheral joints provide the perception of joint position and movement. The sense of proprioception provides dynamic joint stability and various movement skills without the need for conscious planning. It also prevents premature joint degeneration by preventing uncontrolled load on the joints. The cervical proprioceptive system consists of mechanoreceptors of the cervical intervertebral joints, neck muscles and vertebral ligaments, muscle spindles localized in the deep muscles of the cervical spine, and sensitive fibers connecting the neurons in posterior horn of the spinal cord to the neck proprioceptors. Cervical vertebrae, unlike the thoracic and lumbar regions, has an additional importance due to the abundance of mechanoreceptors that provide reflex connections and proprioceptive input with the vestibular central and central nervous systems. In previous studies, it has been shown that the sense of cervical proprioception is impaired in patients with chronic neck pain due to traumatic and degenerative causes. It has been shown that cervical proprioceptive sensory dysfunction in RA causes, vestibular symptoms, changes in contol of eye movements and postural disorders in cervical paravertebral muscles. No study investigating the effect of exercise on cervical proprioception in RA patients was found in the literature. The aim of this study was to determine the effects of cervical stabilization exercises on cervical proprioception in RA patients. The secondary aim of the present study is to evaluate the effects of cervical stabilization exercises on the functional status and quality of life in patients with RA.

Registry
clinicaltrials.gov
Start Date
November 28, 2020
End Date
June 15, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Izmir Katip Celebi University
Responsible Party
Principal Investigator
Principal Investigator

Deniz Bayraktar

Assistant Professor

Izmir Katip Celebi University

Eligibility Criteria

Inclusion Criteria

  • Having been diagnosed with RA according to the ACR 2010 Criteria
  • Being between 18 and 65 years old
  • To be able to understand the given commands

Exclusion Criteria

  • Refusing to participate in the study
  • History of trauma involving the neck
  • Having an orthopedic disorder concerning the neck
  • History of spine surgery
  • Having a disease that affects vestibular system
  • Upper extremity involvement due to a disorder other than RA
  • Being pregnant

Outcomes

Primary Outcomes

Change in Cervical Reposition Error

Time Frame: At baseline and 6 weeks later

Cervical reposition error method will be used to determine the cervical proprioception accuracy. Cervical reposition error will be evaluated in flexion, extension, rotation and lateral flexion directions and will be calculated using a special formula.

Secondary Outcomes

  • Change in Functional Status(At baseline and 6 weeks later)
  • Change in Physical Performance(At baseline and 6 weeks later)
  • Change in Disease Related Quality of Life(At baseline and 6 week later)

Study Sites (1)

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