Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Postoperative Pain Control in Patients Undergoing Thoracotomy: A Prospective, Randomized, Double-blind Controlled Clinical Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Ataturk University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Opioid Consumption
Study Overview
Brief Summary
Thoracotomy surgery is the most painful of all surgical procedures. Inadequate postoperative pain control in these patients may cause serious morbidity related to pulmonary, cardiovascular and emotional systems. Erector Spinae Plane Block (ESPB) was first described in 2016 and, it is frequently used for postoperative analgesia in thoracic surgery. Intravenous lidocaine exhibit analgesic activity through both the peripheral and central nervous system. Intravenous lidocaine has been shown to reduce postoperative pain intensity and accelerate postoperative recovery in many surgeries.
The investigators aimed to compare the effect of lidocaine infusion and erector spinae plane block on postoperative opioid consumption and pain scores.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •American Society of Anesthesiologist's physiologic state I-III patients undergoing thoracotomy surgery
Exclusion Criteria
- •chronic pain, bleeding disorders, renal or hepatic insufficiency, non cooperative patient,
- •Patients with allergies to one of the drugs used in the study.
Arms & Interventions
Group ESPB
Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine and Saline iv. bolus and infusion (same volume as Group Lidocaine)
Intervention: Bupivacaine Hcl 0.25% Inj (Drug)
Group ESPB
Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine and Saline iv. bolus and infusion (same volume as Group Lidocaine)
Intervention: Saline Solution intravenously (Drug)
Group Lidocaine
1.5 mg / kg lidocaine iv. bolus and, 1.5mg / kg / h lidocaine iv. infusion and, Ultrasound-guided erector spinae plane block with 20 ml saline
Intervention: Saline Solution for Block (Drug)
Group Lidocaine
1.5 mg / kg lidocaine iv. bolus and, 1.5mg / kg / h lidocaine iv. infusion and, Ultrasound-guided erector spinae plane block with 20 ml saline
Intervention: Lidocaine (Drug)
Group Control
Ultrasound-guided erector spinae plane block with 20 ml saline and, Saline iv. bolus and infusion (same volume as Group Lidocaine)
Intervention: Saline Solution for Block (Drug)
Group Control
Ultrasound-guided erector spinae plane block with 20 ml saline and, Saline iv. bolus and infusion (same volume as Group Lidocaine)
Intervention: Saline Solution intravenously (Drug)
Outcomes
Primary Outcomes
Opioid Consumption
Time Frame: First 24 hours total opioid consumption
First 24 hours total fentanyl consumption with patient controlled analgesia
Secondary Outcomes
- Visual analog pain score(Postoperative 24 hour)
Investigators
Ahmet Murat Yayik
Medical Doctor
Ataturk University