Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Thoracotomy

Not Applicable

Completed

• Conditions: Thoracic Diseases
• Interventions: Drug: Bupivacaine Hcl 0.25% Inj; Drug: Saline Solution for Block; Drug: Saline Solution intravenously; Drug: Lidocaine

• Registration Number: NCT04221880
• Lead Sponsor: Ataturk University

Brief Summary

Thoracotomy surgery is the most painful of all surgical procedures. Inadequate postoperative pain control in these patients may cause serious morbidity related to pulmonary, cardiovascular and emotional systems. Erector Spinae Plane Block (ESPB) was first described in 2016 and, it is frequently used for postoperative analgesia in thoracic surgery. Intravenous lidocaine exhibit analgesic activity through both the peripheral and central nervous system. Intravenous lidocaine has been shown to reduce postoperative pain intensity and accelerate postoperative recovery in many surgeries.

The investigators aimed to compare the effect of lidocaine infusion and erector spinae plane block on postoperative opioid consumption and pain scores.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-01-07
• Study First Submitted QC: 2020-01-07
• Study First Posted: 2020-01-09
• Study Start: 2021-09-29
• Primary Completion: 2022-03-01
• Study Completion: 2022-03-15
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-13
• Last Update Posted: 2022-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• American Society of Anesthesiologist's physiologic state I-III patients undergoing thoracotomy surgery

Exclusion Criteria

• chronic pain, bleeding disorders, renal or hepatic insufficiency, non cooperative patient,
• Patients with allergies to one of the drugs used in the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group ESPB	Saline Solution intravenously	Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine and Saline iv. bolus and infusion (same volume as Group Lidocaine)
Group ESPB	Bupivacaine Hcl 0.25% Inj	Ultrasound-guided erector spinae plane block with 20 ml %0.25 bupivacaine and Saline iv. bolus and infusion (same volume as Group Lidocaine)
Group Control	Saline Solution for Block	Ultrasound-guided erector spinae plane block with 20 ml saline and, Saline iv. bolus and infusion (same volume as Group Lidocaine)
Group Control	Saline Solution intravenously	Ultrasound-guided erector spinae plane block with 20 ml saline and, Saline iv. bolus and infusion (same volume as Group Lidocaine)
Group Lidocaine	Saline Solution for Block	1.5 mg / kg lidocaine iv. bolus and, 1.5mg / kg / h lidocaine iv. infusion and, Ultrasound-guided erector spinae plane block with 20 ml saline
Group Lidocaine	Lidocaine	1.5 mg / kg lidocaine iv. bolus and, 1.5mg / kg / h lidocaine iv. infusion and, Ultrasound-guided erector spinae plane block with 20 ml saline

Primary Outcome Measures

Name	Time	Method
Opioid Consumption	First 24 hours total opioid consumption	First 24 hours total fentanyl consumption with patient controlled analgesia

Secondary Outcome Measures

Name	Time	Method
Visual analog pain score	Postoperative 24 hour	Post operative pain will be evaluated with a Visual Analogue Scale (VAS) score of 0-10 (0= no pain and 10= worst imaginable pain) at first hour postoperatively.

Trial Locations

Locations (1)

Ataturk University; 🇹🇷 Erzurum, Turkey