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Clinical Trials/NCT05473767
NCT05473767
Completed
Not Applicable

Expanding the Family Check-Up in Early Childhood to Promote Cardiovascular Health of Mothers and Young Children (ENRICH)

University of Pittsburgh3 sites in 1 country117 target enrollmentNovember 18, 2022

Overview

Phase
Not Applicable
Intervention
Family Check-Up
Conditions
Obesity, Maternal
Sponsor
University of Pittsburgh
Enrollment
117
Locations
3
Primary Endpoint
Change in Postpartum Weight Retention
Status
Completed
Last Updated
3 months ago

Overview

Brief Summary

This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on postpartum mothers and infants. The investigators will adapt a cardiovascular health intervention into an evidence-based home visiting program, Family Check-Up to create Family Check-Up Heart. Through a Type 1 hybrid effectiveness implementation design, the pilot study will test the feasibility and effectiveness of Family Check-Up Heart (Family Check-Up Heart, n=100; Family Check-Up, n=50). The investigators hypothesize that Family Check-Up Heart will show comparable levels of engagement and acceptability as Family Check-Up alone, and mothers receiving Family Check-Up Heart will have greater improvements in cardiovascular health at 6 months postpartum compared to Family Check-Up alone.

Detailed Description

This randomized-controlled pilot study will examine the implementation of a cardiovascular health intervention on pregnant and postpartum mothers. The investigators will adapt a cardiovascular health intervention into an evidence-based home visiting program, Family Check-Up to create Family Check-Up Heart. Through a Type 1 hybrid effectiveness implementation design, the pilot study will test the feasibility and effectiveness of Family Check-Up Heart (Family Check-Up Heart, n=100; Family Check-Up, n=50). The investigators hypothesize that Family Check-Up Heart will show comparable levels of engagement and acceptability as Family Check-Up alone, and mothers receiving Family Check-Up Heart will have greater improvements in cardiovascular health at 6 months postpartum compared to Family Check-Up alone. A second goal of the hybrid study is to understand the reach, engagement, and context for implementation of Family Check-Up Heart and gather information for development of the multi-center home visiting model trial. The Family Check-Up Heart program is intended to improve the cardiovascular health of low-income mothers compared to the traditional Family Check-Up and other home visiting programs by incorporating individualized, culturally competent interventions that target diet and exercise, blood pressure control, stress management and self-care, and smoking cessation. The intervention includes cardiovascular assessment and feedback, followed by a tailored treatment program delivered by family coaches in 3-4 week modules to establish goals and track progress. These sessions will work towards obtaining positive cardiovascular health outcomes and empowering mothers of infants to achieve their goals through education and a connection to resources which the investigators hypothesize will also preserve child cardiovascular health. Primary analyses will assess the impact of Family Check-Up Heart on maternal cardiovascular health outcomes when the child is 6 months old compared to Family Check-Up alone.

Registry
clinicaltrials.gov
Start Date
November 18, 2022
End Date
November 22, 2024
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Janet Catov

Associate Professor

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • Adult inclusion criteria:
  • Pregnant women/birthing people or women/birthing people who have delivered in the past 2 months who deliver at Magee or are enrolled in the Women Infants and Children program in Allegheny County.
  • Medicaid-eligible
  • Speak English.
  • Resident of Allegheny County, Pennsylvania.
  • Does not have complex, on-going conditions such as chronic renal or liver disease, systemic lupus erythematosus, cancer or HIV.
  • Participants who consent to enrollment may have their medical history reviewed by study physicians and staff to adjudicate pregnancy outcomes and ensure they meet inclusion criteria before randomization.
  • Child inclusion criteria:
  • Children birth through 2 months who reside in Allegheny County may enroll in the program if their mother is participating in the study.
  • Has a legal guardian who speaks English. This criterion is included because the project's materials and assessments are currently only available in English, with staff only fluent in English.

Exclusion Criteria

  • Pregnant women with complex, on-going conditions such as chronic renal or liver disease, systemic lupus erythematosus, cancer or HIV.
  • Multifetal pregnancies or deliveries.

Arms & Interventions

Family Check Up Control

The Family Check-Up is a home visiting program that typically takes place over the course of 3-5 sessions - An initial interview, assessment, feedback session, and optional treatment sessions. The Family Check-Up is designed to support child development and improve parental well-being.

Intervention: Family Check-Up

Family Check-Up Heart

Family Check-Up Heart combines the traditional Family Check-Up with a heart health component.

Intervention: Family Check Up Heart

Outcomes

Primary Outcomes

Change in Postpartum Weight Retention

Time Frame: Baseline to 6 months post-partum

Weight change from post-delivery to 6 months; both will be measured by the study using validated Bluetooth devices and following standardized research protocols. Mean difference scores are reported.

Secondary Outcomes

  • Weight at 6 Months Postpartum(6 months post-partum)
  • Weight Change From First Measured Prenatal Weight to 6 Months Postpartum(Baseline to 6 months post-partum)
  • Change in Self-reported Pre-pregnancy Weight to 6 Months Postpartum(Baseline to 6 months post-partum)
  • Change in Eating Behaviors(Baseline to 6 months post-partum)
  • Change in Blood Pressure From Post-delivery to 6 Months.(Baseline to 6 months post-partum)
  • Change in Blood Pressure From First Prenatal Visit to 6 Months.(Baseline to 6 months post-partum)
  • Blood Pressure at 6 Months Post-partum(6 months post-partum)
  • BMI at 6 Months Post-partum(6 months post-partum)
  • Change in Physical Activity(Baseline to 6 months post-partum)

Study Sites (3)

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