COvid-19 National Survey for Assessing VIral Spread by Nonaffected CarriErs (CON-VINCE)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,870
- 试验地点
- 1
- 主要终点
- Collection of samples for research
研究概览
简要总结
CON-VINCE (COvid-19 National survey for assessing VIral spread by Non-affected CarriErs) is a national, monocentric, and longitudinal study aiming to evaluate the spread dynamics of the COVID-19 disease within the Luxembourgish population. Participants who are clinically asymptomatic or present with only mild symptoms will be followed up longitudinally, regularly tested for SARS-CoV-2 by RT-PCR, antibody status, and subjected to an epidemiological, clinical and biological phenotyping to better understand the nature, dynamics of infectivity and spread of the virus in the population. CON-VINCE will also track the psychological and socio-economic impact of long-term containment measures on the general population.
详细描述
To capture the dynamics and impact of the virus spread in the Luxembourgish population, data and sample collection is done every two weeks for two months (4 times in total) with a final follow-up one year after the participant's inclusion in the study. Participants complete questionnaires before each sample collection. The baseline questionnaire captures demographic data, medical history, behavioral and psychological data, and socio-economic status. Participants provided information on medical history, history of allergies, smoking, and chronic medication taken regularly. COVID-19-related data and environmental conditions of the household were obtained.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects aged 18 and older of both genders, with a full capacity of consent.
- •SARS-CoV-2-positive individuals with an asymptomatic or oligosymptomatic infection (mild or oligosymptomatic disease course is defined as absence of fever and respiratory distress or cough not attributable to other known chronic disease).
- •OR SARS-CoV-2-negative individuals at the time of inclusion.
- •OR post-infectious SARS-CoV-2-negative individuals with acquired immunity to SARS-CoV-2 and a mild disease course.
排除标准
- •Evolution of the COVID-19 disease requiring a hospital admission before inclusion in the study
- •Presence of fever and respiratory distress/cough at the time of inclusion not attributable to other known chronic disease
结局指标
主要结局
Collection of samples for research
时间窗: 04.2020-05.2021
Samples will be analysed and stored for future research
Prevalence and dynamics of the SARS-COV 2 infection in Luxemburg
时间窗: 04.2020-05.2021
Evaluation of the prevalence by RT-PCR and serology testing
次要结局
- Psycho-social evaluation(04.2020-05.2021)