Pre-emptive Quadratus Lumborum Block for Laparoscopic Bariatric Surgery.A Prospective Randomizes Controlled Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Postoperative pain severity
研究概览
简要总结
The purpose of this study was to determine the effectiveness of pre-emptive Quadratus lumborum block on intra, postoperative pain assessment and opioid requirements in laparoscopic bariatric procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients included in this study are
- •Both genders
- •Age between 18-50 years
- •Those undergoing laparoscopic bariatric surgery (as laparoscopic sleeve gastrectomy or gastric bypass).
- •BMI ≥ 35 Kg/m2 with comorbidity or ≥ 40 Kg/m2 without comorbidity.
排除标准
- •Patients excluded from this study were
- •those with obstructive sleep apnoea and/or Pickwickian syndrome.
- •if the laparoscopy procedure was converted to laparotomy.
- •patients suffering from known coagulation defects.
- •known hypersensitivity to bupivacaine, or those with contraindication to the use of NSAIDS.
- •Presence of sepsis at the site of injection.
研究组 & 干预措施
Group Quadratus lumborum block with bupivacaine
After induction of anesthesia a QLB (quadratus lumborum block) will be performed by using ultrasound machine where a solution of 0.25% bupivacaine 0.2 ml /kg (lean body weight) is used on each side with care not to exceed the toxic dose.
干预措施: US-guided Quadratus lumborum block. (Procedure)
Group Quadratus lumborum block with bupivacaine
After induction of anesthesia a QLB (quadratus lumborum block) will be performed by using ultrasound machine where a solution of 0.25% bupivacaine 0.2 ml /kg (lean body weight) is used on each side with care not to exceed the toxic dose.
干预措施: Bupivacaine (Drug)
Group Quadratus lumborum block with saline
After induction of anesthesia a QLB (quadratus lumborum block) will be performed by using ultrasound machine.A volume of 0.2ml/kg normal saline will given for each side.
干预措施: US-guided Quadratus lumborum block. (Procedure)
Group Quadratus lumborum block with saline
After induction of anesthesia a QLB (quadratus lumborum block) will be performed by using ultrasound machine.A volume of 0.2ml/kg normal saline will given for each side.
干预措施: Saline (Drug)
结局指标
主要结局
Postoperative pain severity
时间窗: 24 hours postoperatively
Assessment of analgesia intraoperatively and for the first 24 hours postoperatively using the numerical ratingscale (NRS)score .The scale ranges from 0 to 10 where 0 indicates no pain and 10 indicates the worst pain imaginable.
次要结局
- Total dose of opioids(24 hours postoperatively.)
- Intraoperative hemodynamics(24 hours postoperatively)
- Postoperative analgesic needs(24 hours postoperatively.)
研究者
Walid Nofal
Clinical professor
Ain Shams University