Influence Continuous Veno-venous Hemodialysis the Autoregulation

Completed

• Conditions: Acute Renal Failure
• Interventions: Procedure: continuous veno-venous hemodialysis

• Registration Number: NCT01376531
• Lead Sponsor: Johannes Gutenberg University Mainz

Brief Summary

The aim of the study is to characterize the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.

Detailed Description

Patients at the intensive care unit who suffered acute renal failure with the need of continuous veno-venous hemodialysis will be investigated with continuous veno-venous hemodialysis and in a time window without continuous veno-venous hemodialysis to investigate the influence of continuous veno-venous hemodialysis on the cerebrovascular autoregulation.

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Study First Submitted: 2011-06-15
• Study First Submitted QC: 2011-06-17
• Study First Posted: 2011-06-20
• Status Verified: 2013-04
• Last Update Submitted: 2013-04-12
• Last Update Posted: 2013-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• acute renal failure
• need for continuous veno-venous hemodialysis
• age >18 Years

Exclusion Criteria

• Sepsis
• Preexisting cerebral illness
• traumatic brain injury
• Meningitis or encephalitis
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
acute renal failure	continuous veno-venous hemodialysis	patients at intensive care unit with definition of acute renal failure and the need for continuous veno-venous hemodialysis

Primary Outcome Measures

Name	Time	Method
Change from Baseline cerebrovascular autoregulation to cerebrovascular autoregulation during continuous veno-venous hemodialysis	1 Year	Is there an influence of continuous veno-venous hemodialysis at the cerebrovascular autoregulation, which would be a side effect with limiting use in patients with brain injury or the need of intensive monitoring of cerebral perfusion pressure in this patients.

Trial Locations

Locations (1)

University medical centre; 🇩🇪 Mainz, Germany