KCT0001088已完成未知
Analysis of Risk Factors for Methicillin-Resistance in Community-associated Staphylococcus aureus Bacteremia
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 250
研究概览
简要总结
- A total of 240 cases of community-acquired Staphylococcus aureus bacteremia were registered in this cohort, and community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) was 20.8% (50 cases). 2) Because the number of cases is less than the target number, we collected more data from previous cohort studies to have sufficient statistical power for risk factor analysis.The enrolled cohorts were the cohort from June 2009 to June 2011 and the cohort from May to December 2012. All of these cohort studies were perfomed using a similar study design. 3) Using these cohorts, this study analyzed the risk factors for methicillin-resistant of Staphylococcus aureus in community. 4) We analyzed community-onset methicillin resistant Staphylococcus aureus bacteremia for clinical application and a total of 1802 cases were included. 5) The risk factors for methicillin-resistance were analyzed.The most powerful predictors of methicillin-resistance were previous isolation of MRSA within 6 months and history of hospitalization or surgery. The negative correlation factors were underlying hematologic disease and endovascular infetion as the primary site of infection. 6) Using these risk factors and negative correlation factors, the scoring system for predicting methicillin-resistance was established in community-onset Sthaphylococcus aureus. With this scoring system, cases were classified into low, intermediate, and high risk groups. 7) The proportion of MRSA in each group was 24.7% (22/89), 39.0% (607/1557) and 78.8% (123/156)
研究设计
- 研究类型
- Observational Study
入排标准
- 年龄范围
- 18(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •Among all adult (>=18years) patients with Staphylococcus aureus bacteremia at participating hospital during the study period
- •1) Patients who agree to the gathering clinical information about S. aureus bacteremia by means of an informed consent.
- •2) Patients who fulfill the criteria of a waiver: Patients who died or transferred within 2 weeks after the onset of bacteremia, an informed consent was waived by institutional review board.
排除标准
- •Patienst who do not agree the participation in this study, except for patients who fulfill the criteria of a waiver of informed consent.
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