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Clinical Trials/NCT00889317
NCT00889317
Completed
N/A

Les Cartes Sensori-motrices De La Parole : Corrélats Neuroanatomiques Des Systèmes De Perception Et De Production Des Voyelles Du Français

University Hospital, Grenoble1 site in 1 country54 target enrollmentMarch 2009

Overview

Phase
N/A
Intervention
Not specified
Conditions
Vowel Perception and Production
Sponsor
University Hospital, Grenoble
Enrollment
54
Locations
1
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Speech develops through a co-structuring of auditory and motor representations, especially in the first years of life during language acquisition. In the present study, we will test by means of functional magnetic resonance imaging whether vowel perception and production might depend on a coordination of auditory and motor, articulatory, cortical maps. The outcome of this study will lead to a better understanding of whether both vowel perception and production are processed in the human brain and will provide important insight into brain-language relationships. Besides new theoretical perspectives on speech perception and production, this project might raise important questions concerning patients with speech disorders by identifying which aspects of speech perception and production are functionally linked.

Detailed Description

The goal of this study is to explore the functional neuroanatomy of vowel processing. To this aim, we will investigate the neural basis of both attentive auditory perception and production of natural French vowels using functional magnetic resonance imaging. More specifically, we will compare vowels that varied along a given phonetic feature dimension while keeping other feature characteristics constant. The phonetic features to be tested are roundedness (rounded/unrounded vowels), place of articulation (front/back vowels) and height (close, close-mid, open-mid vowels). Our study posed three specific questions. First, where exactly in the human brain is the perceptual and motor segregation of different vowel categories accomplished? Second, are these stimulus dimensions implemented topographically in an orthogonal manner, as they vary orthogonally in natural speech? Most specifically, one would expect a topographic segregation between two vowel categories (e.g., front vs back vowels) in both auditory and motor cortices that are characterized by widely distinct acoustic and articulatory values. Third, does these possible sound-related topographic activations in auditory and motor cortices overlap during vowel perception and production? This latter result would support a functional coupling between speech perception and production systems.

Registry
clinicaltrials.gov
Start Date
March 2009
End Date
December 2012
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
University Hospital, Grenoble

Eligibility Criteria

Inclusion Criteria

  • Age between 18 and 60 year-olds
  • Personal health insurance

Exclusion Criteria

  • Contraindications to IRM (Pacemaker, Aneurysm Clip, Heart/Vascular Clip, Prosthetic Valve, Metal Prosthesis, Claustrophobia, Metal fragments in body).
  • Pregnancy / nursing mother
  • Participation to another fMRI study in the last month
  • Speaking or hearing disorders (past/present)
  • Neurological and/or psychiatric disorders (pats/present)
  • Left-handed
  • Non-native French speaker

Outcomes

Primary Outcomes

Not specified

Study Sites (1)

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