Evaluation of ablation lesions using cardiovascular magnetic resonance imaging

Recruiting

Conditions: atrialfibrillation afib
10007521

Registration Number: NL-OMON56080

Lead Sponsor: Sint Antonius Ziekenhuis

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 60

Inclusion Criteria

- Adult patients (age >=18 years old)
- Paroxysmal or persistent AF, meeting criteria of the 2020 ESC Guidelines for
diagnosis and management of atrial fibrillation
- Patients scheduled to undergo catheter ablation for cardiac arrhythmia using
one of the following techniques:
- High power, short duration radiofrequency ablation
- Ultra-low temperature cryoablation
- Pulsed electrical field ablation

Exclusion Criteria

- Known (or suspected) allergic reaction to gadolinium
- Contraindications for MRI (such as claustrophobia, certain implants, devices,
high body mass index).
- Pregnancy or breastfeeding
- Prior intervention in the left atrium (ablation or surgery)

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Incidence and length of gaps in isolation, measured on MR images, for different<br /><br>ablation modalities and strategies</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Additional ablation lesion characteristics measured on MR images (including<br /><br>total ablation lesion length, number of gaps in isolation, location of gaps in<br /><br>isolation, etc.)<br /><br>- Procedural characteristics (including ablation modality, ablation lesion<br /><br>location, ablation energy characteristics per ablation lesion, ablation lesion<br /><br>index, etc.)<br /><br>- Arrhythmia outcomes (including electrocardiographic documentation of atrial<br /><br>arrhythmia, arrhythmia burden on Holter monitoring, etc.)<br /><br>- Quality of life outcomes (AFEQT questionnaire)</p><br>