Clinical trial of evaluation of Methimazole 5% cream effectiveness versus Hydroquinone cream 2% to reduce pregnancy spots (melasma)
Phase 2
- Conditions
- melasma.Chloasma
- Registration Number
- IRCT2016073129145N1
- Lead Sponsor
- Vice chancellor for research, Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Ages from 18 to 50; Normal to dry skin; without comedones
Exclusion criteria: Absence of follow up by patients and not satisfied to continue; Complications such as allergy to topical agent; Pregnancy and lactation; Thyroid disease; Oral contraceptive pills use and other drugs that cause melasma.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hyperpigmentation of face skin. Timepoint: At first and 8 weeks after treatment. Method of measurement: Intensity of the darkening of the face skin compared to other areas of the face with visioface device.
- Secondary Outcome Measures
Name Time Method Satisfaction amount. Timepoint: After completion of treatment. Method of measurement: Comparison of reduction hyperpigmentation by patient, before and after treatment According to schedule.