Study to determine the incidence of hyperchloremia and its complication among ICU patients.
Not Applicable
- Conditions
- Health Condition 1: N179- Acute kidney failure, unspecifiedHealth Condition 2: E878- Other disorders of electrolyte andfluid balance, not elsewhere classified
- Registration Number
- CTRI/2024/01/061201
- Lead Sponsor
- Mr Kallesh R
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
The Patients 18 to 80 years of age.
Duration of stay in the ICU 24 hours to 72 hours.
Patients with sepsis condition with SOFA =2 or APACHE II.
Exclusion Criteria
Patients with symptoms like upper gastrointestinal bleeding, melaena, hematuria, petechiae, or skin lesions that may have hematomas.
Individuals with chronic kidney disease.
Patient admitted with acute renal damage according to RIFLE criteria. patients undergoing peritoneal dialysis or hemodialysis.
Patients taking acetazolamide, methazolamide, dorzolamide, or ethoxzolamide, or any other carbonic anhydrase inhibitor.
Chloride on admission greater than one hundred and six mmol per litter
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method hyperchloremia, hemoglobin, white blood cell count, platelet, urea, creatinine, prothrombin time, INR, Arterial blood gas values (pH, PaO2, PaCO2, HCO3, lactate, base deficit, anion gap), neutrophil lymphocyte ratio, APACHE II score, SOFA score, days of ICU stay, days of ventilator stay, renal replacement therapy, mortality, Procalcitonin, c-reactive protein.Timepoint: 24 hours and 72 hours
- Secondary Outcome Measures
Name Time Method Prolonged ICU stay more than fourteen days.Timepoint: More than 14 days