Pain Trajectories and Predictors After Noncardiac Surgery in Elderly Patients: a Prospective and Observational Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Acute pain trajectories after surgery
研究概览
简要总结
This study will use group-based trajectory modeling to identify the different postoperative pain trajectory groups that exist in a mixed surgical population (non-cardiac surgery) of elderly patients during the first seven days after surgery. The aim of this study is to explore the diversity in the development of postoperative pain among elderly patients and to identify the risk factors for acute pain trajectory after surgery by investigating demographic, psychological, and clinical variables. The predictive effect of different trajectories of early postoperative acute pain on postoperative chronic pain will also be explored.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Scheduled for thoracic, urologic, gastrointestinal, gynecological, liver, biliary/pancreatic, or major orthopedic surgery under general anesthesia
- •Age ≥ 65 years
- •The American Society of Anaesthesiologists(ASA) I to III
- •Duration of hospitalization ≥ 72 hours
排除标准
- •Language disorder;
- •Hearing impairment;
- •Visual impairment;
- •The expected postoperative intubation time is more than 24 hours;
- •Critical events occurred during the perioperative period.
结局指标
主要结局
Acute pain trajectories after surgery
时间窗: Seven days after surgery.
The acute pain trajectories are vectors of 7 numerical pain scores (ranging from 0 ,which indicates "no pain," to 10 , which indicates "pain as bad as you can imagine") taken over 7 days (days 1, 2, 3, 4, 5, 6, 7).
Presence of pain 6 months after surgery assessed using the Brief Pain Inventory.
时间窗: 6 months after surgery
Yes/No
Presence of pain 3 months after surgery assessed using the Brief Pain Inventory.
时间窗: 3 months after surgery
Yes/No
次要结局
- The anxiety score assessed using Amsterdam preoperative anxiety and information scale(day1 before surgery)
- consumption of analgesic drugs(Seven days after surgery)
- The douleur neuropathique 4 questionnaire(DN4)(day1 before surgery)
- Mini-cog(day1 before surgery)
- Geriatrie depression scale，GDS-15(day1 before surgery)
- cumulative illness rating scale for geriatrics，CIR S-G(day1 before surgery)
- The FRAIL Scale(Fatigue, Resistance, Ambulation, Illness and Loss of Weight Index，FRAIL)(day1 before surgery)
- Complications within 7 days after surgery(Seven days after surgery)
- Presence of pain before surgery assessed using the Brief Pain Inventory.(day1 before surgery)
研究者
Feng Gao
Professor
Tongji Hospital