Novel Technique for Botulinum Toxin Injection to Minimize Patient Discomfort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Decrease pain on injection for treatment intervention assessed on a 10 point scale
研究概览
简要总结
This single blinded randomized pilot study was performed on 21 Caucasian females to determine if injections through follicular openings were less painful than traditional injections for cosmetic botulinum toxin type A injections.
详细描述
Objective: To investigate whether injection of botulinum toxin type A is less painful if performed through follicular openings versus traditional non-specific approach.
Design: Prospective, randomized, single-blinded study.
Setting: Academic dermatology department.
Patients: A volunteer sample of twenty female patients aged 25-55 who had no prior history of botulinum toxin injection.
Intervention: Each patient received six randomized injections of botulinum toxin type A (Botox® Allergan). Two injections into the procerus muscle and two into each corrugator muscle. Three of the injections were performed through follicular openings and three were performed traditionally.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •No prior history of botulinum toxin
- •Age 25-55
排除标准
- •Prior history of botulinum toxin
- •Neuromuscular disorders
- •Aminoglycoside therapy
结局指标
主要结局
Decrease pain on injection for treatment intervention assessed on a 10 point scale
时间窗: At time of intervention
次要结局
未报告次要终点
研究者
David M. Ozog
Chair-Dermatology
Henry Ford Health System