Effect of Lidocaine and Adrenaline Soaked Gauze Versus Normal Saline Soaked at Skin Graft Donor Site of Thigh: A Randomized Control Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Post operative bleeding
研究概览
简要总结
Investigator is studying the effects of Lidocaine and Adrenaline Soaked Gauze vs Normal Saline Soaked Gauze at Skin Graft Donor Site of Thigh.
Haemostatic effect, epithelization and post operative pain will be assessed on follow up.
详细描述
After admission participants will be randomized either to be in Group A or Group B. Closed envelop technique will be used for random assignment of the patients.
Group A will be receiving 2% lidocaine and 1:100,000 adrenaline soaked gauze while group B will be given only normal saline soaked gauze at donor-site for ten minutes.
The primary end point of study is intraoperative bleeding. The secondary end points of study include no. of dressings required in first 24 hours after surgery, donor site epithelization at 14th post-operative day, post-operative pain in first 24 hours after surgery along with systemic analgesia requirement after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
Patients will be recruited in the study by closed envelope technique and the study will be single blinded.
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •• Patients of both the gender of age > 15 years
- •Multiple donor-sites
排除标准
- •Bleeding disorder
- •Concomitant injuries
- •Donor site other than thigh
- •Previously harvested donor-site
- •Patients on antiplatelet medications
研究组 & 干预措施
Group B ( Normal Saline)
Group B patients will receive normal saline soaked gauze over skin graft donor site of thigh intraoperatively for 10 minutes. After 10 minutes this dressing will be removed and sufratul dressing will be applied over donor site
干预措施: Normal saline (Drug)
结局指标
主要结局
Post operative bleeding
时间窗: 24 hours
post operative bleeding will be assesd in post operative period by number of dressings required.
Intra operatieve bleeding
时间窗: per operative
Intra-operative Bleeding from donor site of graft will be assessed per operatively as being normal or more than normal.
Post operative pain
时间窗: 24 hours
post operative pain will be assessed in the post operative period by visual analog score. Score ranges from 0 to 10 with 0 indicating no pain whereas 10 is worst pain.
Analgesia requirement
时间窗: 24 hours
Post operative analgesia requirement of patient will be observed by number of medications required
次要结局
- Epithelization of donor site(14 days)
研究者
Zaara Zahid
Principle investigator
Dow University of Health Sciences