IRCT20130719014056N14Not yet recruitingPhase 2
Comparing the effects of modafinil, methylphenidate and aminophylline on the level of consciousness and weaning from mechanical ventilation in patients with acute traumatic brain injury in intensive care unit
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Not yet recruiting
- Enrollment
- 189
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 16 years to 50 years (—)
- Sex
- All
Inclusion Criteria
- •GCS less than 10
- •Age between 16 and 50 years
- •Both genders
- •History of acute traumatic brain injury
- •Absence of space-occupying lesion in brain CT scan (chronic hematoma, tumor)
- •Absence of seizure history
- •No addiction to psychoactive substances and narcotics
- •No history of amphetamine use
- •No history of hypertension, ischemic heart disease, diabetes mellitus, and liver and kidney disease
- •Heart rate less than 120 times per minute
- •Absence of sepsis or infection in any part of the body
Exclusion Criteria
- •Convulsions
- •Evidence of drug sensitivity
- •Lack of consent of the patient to participate in the study
Investigators
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