Investigation of efficacy of novel first aid treatments for envenomation from snake bite

Not Applicable

Withdrawn

• Conditions: Envenomisation by snakebite; Injuries and Accidents - Other injuries and accidents

• Registration Number: ACTRN12613000879763
• Lead Sponsor: Dr Paul Thomas

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-08-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

18 years or older
Able to give informed consent
Willing to undergo injection of radiotracer and lymphoscintigraphy
Willing to receive topical therapy on lower limbs
Able to walk gently on a treadmill in 5 minute sessions every ten minutes until an exercise end point in reached

Exclusion Criteria

Pregnancy
Breast feeding
History of lymphatic disease
Lower limb vascular insufficiency (venous or arterial)
Previous trauma or major surgery to the lower limb
Skin at risk of injury from pressure pad or cold pack
Peripheral sensory neuropathy
Diabetes Mellitus
Ankle oedema
Allergy to radiotracer
Severe osteoarthritis or any possible impairment to mobility
Unable to give informed consent
Institutionalised
Prisoners
Participants requiring interpreters or attendants, those with LOTE, cognitive impairment or highly dependent on medical care.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the ability of cold packs to slow the lymphatic flow in the human model of a simulated snake bite using lymphoscintigraphy[Utilising gamma camera imaging, the primary time point will be the comparison of the time taken for the radiotracer to be visualised in the inguinal node and liver between the baseline study and the cold pack intervention study.];To assess the ability of a pressure pad to slow the lymphatic flow in the human model of a simulated snake bite using lymphoscintigraphy[Utilising gamma camera imaging, the primary time point will be the comparison of the time taken for the radiotracer to be visualised in the inguinal node and liver between the baseline study and the pressure pad intervention study.]

Secondary Outcome Measures

Name	Time	Method
To determine whether the pressure pad method would also allow a snake bite victim to walk safely. [Utilising gamma camera imaging, the secondary time point will be the comparison of the time taken for the radiotracer to be visualised in the inguinal node and liver between the baseline study, the pressure pad intervention study and the pressure pad with treadmill walking intervention study.]