NCT07704255招募中4 期
Study on the Effect of Fecal Microbiota Transplantation on Eradication of Refractory Helicobacter Pylori Infection
Sichuan Provincial People's Hospital1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2026年7月20日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Whether Hp is successfully eradicated
研究概览
简要总结
To determine whether regulating the gut microbiota can contribute to the eradication of refractory H. pylori infection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1. Ages 18-70
- •2. Hp infection treatment failed ≥4 times with guidelines-recommended therapies
- •3. Patients with early gastric cancer, peptic ulcer, gastric MALT lymphoma, atrophic gastritis and other diseases requiring the eradication of Hp.
排除标准
- •1. Antibiotics and bismuth were taken within 4 weeks before this treatment; Or had taken PPI, H2 receptor antagonist, P-CAB within 2 weeks prior to treatment;
- •2. Pregnant or lactating women;
- •3. Those who are allergic to the investigational drugs used in this test or have contraindications;
- •4. Participated in other drug trials within 3 months before the treatment of this trial;
- •5. There are other serious diseases that affect the evaluation of this study at the same time, or they cannot correctly express their own complaints and cannot cooperate;
- •6. Subjects with dysphagia;
- •7. Patients with malignant tumors, serious concomitant diseases, severe ulcer bleeding or perforation;
- •8. Patients judged by the investigator to be unsuitable for clinical trials.
- •9. Those who do not want to sign the informed consent for the study.
结局指标
主要结局
Whether Hp is successfully eradicated
时间窗: 2years
The successful eradication of Hp was determined by 13C urea breath test, immunohistochemical staining of Hp and Hp culture.test, immunohistochemical staining of gastric mucosa and Hp culture
次要结局
未报告次要终点
研究者
Gao Caiping
Chief physician
Sichuan Provincial People's Hospital
研究点 (1)
Loading locations...
相似试验
尚未招募
2 期
Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)CirrhosisHepatic EncephalopathyNCT07528690VA Office of Research and Development162
进行中（未招募）
不适用
Fecal Microbiota Transplantation Intervention on Microbiota Composition and Insulin Sensitivity in DiabetesNCT07375797Central Jutland Regional Hospital16
招募中
2 期
Fecal Microbiota Transplantation for Steroid-Refractory Acute GI GVHDNCT07364617Chang Gung Memorial Hospital35
尚未招募
不适用
Effects of Fecal Microbiota Transplantation in Patients With Type 2 Diabetes and Coronary Artery Disease (CAD-Microbiome) - A Pilot StudyCoronary Artery DiseaseNCT07421947University of Zurich30
尚未招募
2 期
Fecal Microbiota Transplant(FMT) Combination With Tislelizumab in Advanced or Metastatic NSCLCNCT07432984Se-Hoon Lee15