Microcirculation in Perforator Flaps. Enhancing Tissue Survival
Overview
- Phase
- Early Phase 1
- Intervention
- Not specified
- Conditions
- Reconstructive Surgery
- Sponsor
- Oslo University Hospital
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Mean pixel intensity using dynamic laser-induced-fluorescence-videoangiography
- Last Updated
- 15 years ago
Overview
Brief Summary
The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.
Detailed Description
Perforator flaps are increasingly used in reconstructive surgery both as pedicled and free flaps, mostly because of reduced donor site morbidity and superior aesthetic result. However, the there is still much to learn about the hemodynamic changes within these flaps.The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients submitted to elective abdominoplasty
Exclusion Criteria
- •body mass index \< 30 kg/m2
- •morbidly obese
- •patients with comorbidity such as diabetes
- •vascular disease
- •patients \< 18 years, and patients using anti-coagulant therapy
- •severe hepatic insufficiency were excluded and a history of allergic reactions to ICG and iodide.
Outcomes
Primary Outcomes
Mean pixel intensity using dynamic laser-induced-fluorescence-videoangiography
Time Frame: dec. 2008--des 2010
Perfusion measurements were conducted intraoperatively by assessing microcirculation using the technique of dynamic laser-induced-fluorescence-videoangiography (IC-VIEW, PULSION Medical Systems AG, Munich, Germany).